Vol. 79, No. 2, 2024

Moscow University Chemistry Bulletin

Modern Methods of Aptamer Chemical Modification and Principles of Aptamer Library Selection

M. F. Subach, M. G. Khrenova and M. I. Zvereva p. 79 abstract

Computer Modeling of the Mechanisms of Enzymatic Reactions: Lessons from 20 Years of Practice

M. G. Khrenova, T. I. Mulashkina, A. M. Kulakova, I. V. Polyakov and A. V. Nemukhin p. 86 abstract

High Throughput Screening in Drug Discovery: Problems and Solutions

D. M. Hushpulian, I. N. Gaisina, S. V. Nikulin, T. A. Chubar, S. S. Savin, I. G. Gazaryan and V. I. Tishkov p. 93 abstract

Protein Engineering of Bst Polymerase for Isothermal Amplification Purposes

A. S. Cherkashina, O. O. Mikheeva and V. G. Akimkin p. 105 abstract

Methylation of Coproporphyrin as a Protective Mechanism in Mycobacteria under Adverse Conditions

D. I. Bagaeva, G. R. Demina, M. O. Agaphonov, A. P. Savitsky, A. S. Kaprelyants and M. O. Shleeva p. 110 abstract

Post-Translational Modifications of the Sulfhydryl Group of the Cysteine Residue of Glyceraldehyde-3-phosphate Dehydrogenase

V. I. Muronetz, M. V. Medvedeva and E. V. Schmalhausen p. 115 abstract

Strategies of N-Glycosidic Bond Cleavage by DNA Repair Enzymes

A. V. Endutkin and D. O. Zharkov p. 121 abstract

Protein Engineering of Lactate Oxidase

E. D. Belyaeva, N. V. Komarova and A. E. Kuznetsov p. 127 abstract

Application of MF3 Microbial Recombinant Protein in Refolding of Plant Chitinase

A. M. Rozhkova, Yu. A. Denisenko, I. G. Sinelnikov, I. N. Zorov, D. V. Erokhin and V. G. Dzhavakhia p. 133 abstract

Biocatalysis in the Degradation of Synthetic Polymers

O. V. Maslova, O. V. Senko, N. A. Stepanov, I. V. Lyagin and E. N. Efremenko p. 140 abstract