Contents

Russian Journal of Bioorganic Chemistry

Vol. 50, No. 6, 2024

Synthesis and Cytotoxicity Evaluation of 2-(4-((1,3-Dioxoisoindolin-2-yl)methyl)phenyl)-N-phenyl-thiazole-4-carboxamide Derivatives as Apoptosis Inducers with Potential Anticancer Effects

Leila Hosseinzadeh, Ghazal Mahmoudi, Masoumeh Mahsa Mohammadi, Amin Hosseini, Hossein Malekshahi, and Alireza Aliabadi p. 2095  abstract

Nutritional Benefits of Fucoidan and Its Applications (A Review)

Emmanuella T. Bulya, Rita S. Alqubelat, and A. Ranga Rao p. 2107  abstract

Convenient Synthesis, Antibacterial Activity, and In Silico Studies of Novel 6-Phenoxy-4,5-dihydro-1,2,6-oxazaphosphinine 6-Oxides

A. Wahbi, M. A. Dridi, I. Dridi, H. Alimi, and S. Touil p. 2134  abstract

Novel Pyridazine-3(2H)-one Derivatives as SARS-CoV-2 Inhibitors: Design, Synthesis, Characterization, Molecular Docking, and Their In Silico ADMET Studies

Kilol M. Rabara, Jaydeep N. Lalpara, and Gaurang G. Dubal p. 2149  abstract

Synthesis and Biological Evaluation of New 1,2,3-Triazole-piperzine-quinazolines as Potent Anticancer Agents

G. Swetha, and Naseem p. 2162  abstract

Design and Synthesis of Some New Quinoxaline-Thiazole-Benzamide Hybrids: In Vitro Anticancer Activity and Their Molecular Docking Studies

Gouthami Dasari, Madhuri Pandiri, Vinitha Badithapuram, Rajender Reddy Karnekanti, Jyothi Mandala, and Srinivas Bandari p. 2171  abstract

Expeditious Synthesis, Characterization, and Antimicrobial Assessment of Thiazole Derivatives

Shantaben K. Kangad, Sachin M. Sitapara, and V. N. Patolia p. 2182  abstract

Blood Erythrocytes—a Biological Model for Evaluating Antioxidant Activity of Chemical Compounds (A Review)

O. G. Shevchenko p. 2191  abstract

Universal Immune Learning Ability in Immune and Non-Immune Cells (A Review)

I. V. Alekseenko, L. G. Kondratyeva, I. P. Chernov, and E. D. Sverdlov p. 2209  abstract

Investigation of Novel Thiazolin-2,4-diones: Synthesis, Biological Evaluation, and Docking Studies for Enhanced Insights

M. Yadav, R. Dinkar, S. N. Mali, S. Sharma, and A. Jain p. 2219  abstract

Synthesis of Eugenol-Derived Coumarins as Broad-Spectrum Biosafe Antimicrobial Agents

Islam Khalid Kamal, Atyaf Talal Mahmood, and Yasser Fakri Mustafa p. 2240  abstract

Coumarin Backbone as a Door-Opening Key for Investigating Chloroxylenol as Oral Antimicrobial Agents: an In Vitro–In Silico Study

Atyaf Talal Mahmood, Islam Khalid Kamal, and Yasser Fakri Mustafa p. 2252  abstract

Adjuvant Effect of Benzo(a)pyrene on Specific IgE Production and B-Cell Subpopulations in Lungs, Regional Lymph Nodes, and Spleen in Mouse Allergy Model

D. B. Chudakov, O. A. Shustova, M. A. Strel’tsova, A. A. Generalov, R. A. Velichinskii, O. D. Kotsareva, and G. V. Fattakhova p. 2269  abstract

Covalent Epidermal Growth Factor Receptor (EGFR) Inhibitors in Targeted Therapy of Drug-Resistant Non-Small Cell Lung Cancer (A Review)

A. B. Shvetsov, and A. V. Semenov p. 2283  abstract

Cognitive Improvement Effects of Polymer-Based Microencapsulated Celecoxib in a Rat Model of Alzheimer’s Disease

Rajendra Herur Vishnumurthy, M. Gnana Ruba Priya, Prashant Tiwari, and Viswas Raja Solomon p. 2312  abstract

Exploring the Mechanisms of Indole-Oxadiazole Benzamide Hybrids as Tyrosinase Inhibitors: Insights from Lineweaver-Burk Plot Analysis and Computational Studies

M. Nazir, U. Khan, M. Jahangir, K. Hayat, S. A. R. Bokhari, A. Shakoor, E. Ahmad, and H. M. F. Haider p. 2325  abstract

Synthesis and Evaluation of NH2 and SH Linker Free Benzothiazole-Triazole Compounds: Insights into Antimicrobial Efficacy

Aamir R. Shama, Mehulkumar L. Savaliya, and Snehal Lokhandwala p. 2344  abstract

Inhibition of Dipeptidylpeptidase-IV by (2S)-Cyanopyrrolidine Inhibitors of Prolyl Endopeptidase

G. I. Makarov, N. N. Zolotov, and V. F. Pozdnev p. 2366  abstract

New Cationic Carbohydrate-Modified Amphiphiles and Liposomes for Effective Delivery of Short Nucleic Acids into Eukaryotic Cells

E. V. Shmendel, A. O. Buyanova, O. V. Markov, N. G. Morozova, M. A. Zenkova, and M. A. Maslov p. 2379  abstract

Innovative Nanoformulation Strategies of Hesperetin and Hesperidin: Pioneering Advances in Pharmaceutical Applications (A Review)

Samet Poyraz, Mehmet Cimentepe, Ozge Ozturk Cimentepe, and Metin Yildirim p. 2397  abstract

Update on Chemistry and Biological Activities of Naturally Occuring Isocoumarins and 3,4-Dihydroisocoumarins (A Review)

Ghulam Shabir, Aamer Saeed, Moonsa Haq, Fatima Choudry, Rimsha Kiran, Madiha Irfan, Shaneeza Tariq, and Hesham R. El-Seedi p. 2426  abstract

The Role of Estrogen Receptors in the Therapeutic Effect of Oxyresveratrol, Phytoestrogen, During, and After Oxidative Stress

Cansu Kara Oztabag, Akif Hakan Kurt, Lokman Ayaz, and Mehmet Ali Sungur p. 2445  abstract

Adaptation of the Protocol of the Automated Solid-Phase Phosphoramidite Synthesis of Oligodeoxyribonucleotides for Preparing Their N-Unsubstituted Phosphoramidate Analogs (P–NH2)

E. A. Malova, I. A. Pyshnaya, M. I. Meschaninova, and D. V. Pyshnyi p. 2455  abstract

Cu-Metal Catalyst Based Click Chemistry: Synthesis, Characterization, Molecular Docking, and Antibacterial Evaluation of Triazole Derivatives

Sachin M. Sitapara, Jignesh H. Pandya, Shantaben K. Kangad, Deepika Maliwal, Raghuvir R. S. Pissurlenkar, Dharmesh K. Katariya, and Sandeep G. Chovatiya p. 2473  abstract

Design, Synthesis, In Silico Studies, and Anticancer Activity of Novel Nitrobenzene Thiazolyl Hydrazones against the EGFR

Sonali S. Shinde, Jaydeo T. Kilbile, Shankar Thapa, Mahalakshmi S. Biradar, Sachin S. Bhusari, and Pravin S. Wakte p. 2483  abstract

Molecular Biological Approaches to Human Oocyte Developmental Competence Prognosis

A. R. Smolyaninova, E. O. Bashendjieva, N. V. Ponomartsev, D. I. Ostromyshenskii, J. A. Tatishcheva, A. S. Kalugina, and N. I. Enukashvily p. 2499  abstract

Changes in the Heterogeneity of MSC Subpopulations During Replicative Senescence as Seen from Single-Cell Speed Measurements

A. V. Lukacheva, A. I. Gorb, A. S. Musorina, D. V. Kriger, G. G. Poljanskaya, and D. E. Bobkov p. 2509  abstract

Exopolysaccharide from Rhizopus nigricans Modulates Antitumor Immune Responses by Promoting Tumor-Associated Macrophage Polarization toward the M1 Phenotype in C57BL/6J Mice

Guozheng Qin, Ping Li, Mingrui Zhang, Zhengzhi Yu, Xuebin Shen, Wanyun Zhang, Yuyan Zhou, Pingchuan Yuan, Yuhan Yang, Chunyan Liu, and Guodong Wang p. 2519  abstract

Antioxidant and Antibiofilm Activity of Laccase-Mediated Oxidized Products of Ferulic Acid

Monica Ramasamy, Meenalokshini Ponnusamy, Sharulatha Venugopal, Aishwarya Vetrivel, and Rajeswari Murugesan p. 2529  abstract

Vitamin B12 in Drug Delivery Systems (A Review)

A. A. Skuredina, D. E. Ialama, and I. M. Le-Deygen p. 2540  abstract

Comparison of Antisense Oligonucleotides, DNAzymes, and Their Bivalent Forms in RNAse H Dependent Cleavage of Folded RNA

M. V. Dubovichenko, V. Nnanyereugo, G. A. Bobkov, A. A. ElDeeb, and D. M. Kolpashchikov p. 2558  abstract

Porphyrins as Polyfunctional Ligands for Binding to DNA. Prospects for Application (A Review)

N. Sh. Lebedeva, and E. S. Yurina p. 2567  abstract

Ultrasound Assisted Synthesis of Pyran Derivatives Catalysed by Uranyl Nitrate and Their Molecular Docking Against Glycogen Synthase Kinase-3 Beta Receptor

K. Venkatesan, T. Srinivasa Rao, V. Sridhar, J. Yacobe, T. V. V. Satyanarayana, and M. Pasupathi p. 2580  abstract

Production and Refolding of the Ligand-Binding Domain of TrkA Receptor with the Extracellular Juxtamembrane Region

D. R. Bedanokova, M. V. Goncharuk, A. V. Shabalkina, V. A. Lushpa, A. S. Arseniev, E. V. Bocharov, K. S. Mineev, and S. A. Goncharuk p. 2589  abstract

Metabolic Profile of Transgenic Birch Plants with the Conifer Cytosolic Glutamine Synthetase Gene GS1

V. G. Lebedev p. 2596  abstract

Structural Analysis of the LZTFL1 Protein by Principal Component Analysis (PCA-seq)

I. I. Khegai, X. Yu, and V. M. Efimov p. 2611  abstract

Synthesis and Cytotoxicity Evaluation of Maleopimaric and Dihydroquinopimaric Esters and Amides

E. V. Tretyakova, and S. R. Sharafutdinova p. 2618  abstract

Acute Toxicity Evaluation of Pyridine Derivatives of 3,4-Dihydroquinoxalin-2-one and 3,4-Dihydro-2H-1,4-benzoxazin-2-one

S. A. Ternovskaya, V. S. Vlasenko, A. N. Novikov, N. A. Dengis, A. L. Stalinskaya, and I. V. Kulakov p. 2627  abstract

Non-Agglomerated Oligonucleotide-Containing Nanocomposites Based on Titanium Dioxide Nanoparticles

M. N. Repkova, O. Yu. Mazurkov, E. I. Filippova, N. A. Mazurkova, Yu. E. Poletaeva, E. I. Ryabchikova, B. F. Zarytova, and A. S. Levina p. 2634  abstract

Expression of the Extracellular Domain of Mouse PD-L1 and Production of Antibodies to PD-L1

M. S. Goryunova, D. Yu. Ryazantsev, E. E. Petrova, V. V. Kostenko, A. O. Makarova, R. V. Kholodenko, E. V. Ryabukhina, D. V. Kalinovsky, O. D. Kotsareva, and E. V. Svirshchevskaya p. 2644  abstract