Contents

Russian Journal of Bioorganic Chemistry

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Vol. 45, No. 4, 2019

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Immune Checkpoints of the B7 Family. Part 1. General Characteristics and First Representatives: B7-1, B7-2, B7-H1, B7-H2, and B7-DC

A. I. Chapoval, S. P. Chapoval, N. S. Shcherbakova and D. N. Shcherbakov p. 225  abstract

The Synthesis and Biological Activity of 3,3'-Dimethyl-L-Selenocystine, a New Selenocystine Derivative

P. A. Poluboyarinov, N. A. Golubkina, A. A. Aniskov, I. J. Moiseeva, N. N. Glebova and V. I. Shvets p. 241  abstract

Synthesis and Antitumor Activity of Conjugates Based on the Phe-D-Trp-Lys-Thr Peptide Fragment of Somatostatin

D. V. Avdeev, M. V. Sidorova, M. V. Ovchinnikov, N. I. Moiseeva, V. N. Osipov, A. N. Balaev and D. S. Khachatryan p. 248  abstract

Exploration of Novel MTH1 Inhibitors Using Fragment-Based De Novo Design, Virtual Screening, and Reverse Virtual Screening Methods

Xin-yu Zhao, Kai Liu, Xiao-li Wang, Ri-lei Yu and Cong-min Kang p. 253  abstract

Amplification Efficiency and Substrate Properties of Fluorescently Labeled Deoxyuridine Triphosphates in PCR in the Presence of DNA Polymerases without 3'-5' Exonuclease Activity

S. A. Lapa, O. S. Volkova, M. A. Spitsyn, V. E. Shershov, V. E. Kuznetsova, T. O. Guseinov, A. S. Zasedatelev and A. V. Chudinov p. 263  abstract

Induction of Apoptosis in SKOV3 and DNA Binding by Cobalt(III) Polypyridyl Complexes

Ch. Ravi, Ravi Kumar Vuradi, Srishailam Avudoddi, M. Ramchander and S. Satyanarayana p. 273  abstract

Inhibitory Effect of Transcription Factor YB-1 in the Development of Signal from an Innate Immunity Receptor NOD2

L. G. Alekseeva, A. G. Laman, A. O. Shepelyakovskaya, N. S. Plekhanova and V. T. Ivanov p. 285  abstract

Synthesis and Cytotoxicity of О- and N-Acyl Derivatives of Azepanobetulin

T. V. Lopatina, N. I. Medvedeva, I. P. Baikova, A. S. Iskhakov and O. B. Kazakova p. 292  abstract

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