Contents

Russian Journal of Bioorganic Chemistry

Vol. 52, No. 2, 2026

RESEARCH PAPER

4Bromobenzenesulfonate Schiff Base Derivatives Cause DNA Degradation in Bacterial Cells

Bengü Ergüden and Yasemin Ünver p. 27  abstract

Benzo[g]quinoline Derivatives as Potent α-Glucosidase Inhibitors: Synthesis, Characterization, and In Vitro Inhibition

Shantaben K. Kangad, Sachin M. Sitapara, and V. N. Patolia p. 28  abstract

Synthesis and Antimicrobial Evaluation of Quinoline-Pyrazolone Hybrid Derivatives as Potential Therapeutic Agents

Dharmesh Katariya, Pankaj Solanki, Kavan Andharia, Ramesh Kothari, Bharat Kataria, Manish Shah, and Ranjan Khunt p. 29  abstract

Emodin Alleviates Alcohol-Induced Liver Fibrosis by Modulating Extracellular Matrix and Inhibiting the TGF-β1/Smad3 Signaling Pathway

Bingbing Zhang, Mengli Yang, Sanqiang Li, Longfei Mao, Xiaomin Hong, Renli Luo, Ruifang Li, and Qinyi Cui p. 30  abstract

Synthesis of Fused Benzoxazole-Imidazo[1,2-c][1,2,3]triazole Hybrids in PEG-400 and Evaluation of Their Anticancer Activity In Vitro and In Silico

Muralimohanarao Vana, Ranadheerkumar M, Tonukunuru Gopikishan, and Harbeer Singh p. 31  abstract

New 1,3-Benzoxazol-2(3H)-one Aroylhydrazone and Acetamide Hybrids as Promising Acetylcholinesterase Inhibitors: Microwave Synthesis, Structure–Activity Relationship, and Drug-Likeness Evaluation

Fatih Yilmaz, Gülay Akyüz, Nedime Çalışkan, and Emre Menteşe p. 32  abstract

Exploring the Antidiabetic Potential of Newly Synthesized α-Aminophosphonate–Coumarin Hybrids: Design, Synthesis, In Silico Docking, and Biological Evaluation

Rashmi S. Chouthe, Rahul P. Kshirsagar, Jaiprakash N. Sangshetti, Manoj G. Damale, and Hemant D. Une p. 33  abstract

Water-Mediated Synthesis of Oxindole-Embedded Chalcone Hybrids: Anticancer Evaluation and Computational Insights

Jeky C. Makwana, Ranjitsinh C. Dabhi, Unnati P. Patel, Zeelu M. Patel, Devashish Mehta, Nandan Dixit, Saumya Patel, Rakesh M. Rawal, and Jayesh J. Maru p. 34  abstract

Synthesis and Study of Enzymatic Stability of Phosphinic Pseudo-Pro-Gly-Tripeptide Derivatives of Dopamine and Serotonin

V. P. Shevchenko, M. E. Dmitriev, K. V. Shevchenko, A. V. Borodachev, I. Yu. Nagaev, D. E. Ivanov, L. A. Andreeva, V. V. Ragulin, and N. F. Myasoedov p. 35  abstract

I. Synthesis and Antioxidant Activity of Hydrazineсarbothioamides Based on 6-Methyluracil and Hydrazines

I. B. Chernikova and T. A. Sapozhnikova p. 36  abstract

Nitrogen-Containing Heterocycles as Novel GPR109A Agonists for the Treatment of Dyslipidemia

Prajakta B. Kothawade, Asha B. Thomas, Vrushali Balchim, Sohan S. Chitlange, Kiran Bharat Lokhande, and Kakumani Venkateswara Swamy p. 37  abstract

Mechanisms of Action of Plant Proteins That Bind and Transfer Key Regulatory Hydrophobic Compounds

D. S. Veselov, E. I. Finkina, G. R. Akhiyarova, G. H. Vafina, L. B. Vysotskaya, T. V. Ovchinnikova, and G. R. Kudoyarova p. 38  abstract

Pyridoxine-Based Methylpyridinium Salts: Synthesis and Biological Activity

M. A. Belova, A. D. Strelnik, N. V. Shtyrlin, S. V. Sapozhnikov, S. A. Ivanov, M. N. Agafonova, D. V. Ivanova, E. S. Bulatova, D. Yu. Grishaev, Yu. V. Badeev, O. I. Gnezdilov, O. V. Bondar, O. S. Vasilieva, M. N. Mansurova, and Yu. G. Shtyrlin p. 39  abstract

Design, Synthesis, In Vitro, and In Silico ADME/Toxicity Study of Novel Methoxyphenyl-Substituted Thiazole–Triazole Hybrids as Antitubercular Agents

Prashant J. Burange and Pinkal H. Patel p. 40  abstract

REVIEW PAPER

IR700DX-Based Antibody Conjugates: a Unique Tool for Targeted Cancer Phototherapy

T. D. Nikitin, E. L. Gulyak, and K. A. Sapozhnikova p. 41  abstract

RESEARCH PAPER

Design, In Silico, Synthesis, and Biological Evaluation of Some N-(Arylidene)-5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amines as Oligosaccharide-Based α-Amylase Inhibitors

Dharmvir Singh, Pankaj Kumar, Sunil Shukla, Ramchander Khatri, Mohammad Ovais Dar, Sandeeep Kumar, Tanuj Hooda, and Amit Lather p. 42  abstract

REVIEW PAPER

Evaluation of the Anticancer Activity of Sulfonamides and Their Metal Complexes as Promising Therapeutic Agents

Pandichamy J. Subhashini, Palanisamy Chandrabooma, and Maruthapillai Gowri p. 43  abstract

RESEARCH PAPER

Structure and Isoforms of Surfactin Produced by Mutant Strain Bacillus subtilis PY79sfp+

E. Yu. Lindin, V. S. Trefilov, M. B. Viryasov, M. V. Serebryakova, A. L. Ksenofontov, T. S. Oretskaya, and E. A. Kubareva p. 44  abstract

REVIEW PAPER

Reactivity of (–)-Shikimic Acid as the Basis of Its Biological Role and a Template for the Development of Antiviral Agents: a Case Study of Oseltamivir Phosphate

S. V. Smirnov and V. A. Kurkin p. 45  abstract

Heterocyclic Scaffolds in Cardiovascular Drug Development: The Emerging Role of Pyridazine Derivatives

M. Asif, P. Chandra, and K. K. Joshi p. 46  abstract

Adenosine Pathway of T Cell Regulation with a Chimeric Antigen Receptor

K. A. Mironova, A. D. Zotova, and I. E. Deyev p. 47  abstract

PR-10 Allergens: From the Molecular Basis of Cross-Reactivity to Current and Future Immunotherapy Strategies

I. V. Bogdanov, E. I. Finkina, D. N. Melnikova, A. E. Potapov, and T. V. Ovchinnikova p. 48  abstract

Neurotrophin-4: Discovery, Tissue Distribution, and Biological Effects

T. A. Gudasheva, N. I. Sokolenko, K. N. Koliasnikova, P. Yu. Povarnina, and V. L. Dorofeev p. 49  abstract

RESEARCH PAPER

Interaction of Monoclonal Antibodies Against Individual Parts of Bacillus cereus Hemolysin II with a Pore Formed by the Toxin

N. V. Rudenko, A. P. Karatovskaya, O. S. Vetrova, A. V. Zamyatina, A. S. Nagel, Zh. I. Andreeva-Kovalevskaya, A. V. Siunov, F. A. Brovko, and A. S. Solonin p. 50  abstract

REVIEW PAPER

Alternative Methods for Bacterial Biofilm Elimination Using Metal/Metal Oxide Nanoparticles

P. A. Demina and A. N. Generalova p. 51  abstract

RESEARCH PAPER

Proteolytic Activity of Oligopeptidase B against Tryptophan-Rich Antiprotozoal Peptides

A. G. Mikhailova, D. E. Petrenko, D. M. Karlinsky, V. V. Britikov, E. V. Britikova, and T. V. Rakitina p. 52  abstract

Carboxyl Derivatives of Chloramphenicol with Stable Linkers in the Side Chain and Their Immunoreactive Conjugates with Horseradish Peroxidase

O. S. Kuprienko, A. L. Hurski, A. I. Zilberman, I. I. Vashkevich, and O. V. Sviridov p. 53  abstract

RESEARCH PAPER

1,8-Naphthalimide-Based Fluorescent Bisphosphonates: Molecular Design, Spectral-Luminescent Properties, and Osteotropic Targeted Delivery Systems

D. Yu. Yuriev, I. V. Barabanshchikov, V. A. Strukova, S. V. Tkachenko, A. A. Pakhomov, S. M. Deev, M. G. Akimov, N. D. Ternovaya, G. D. Sherstyanykh, V. A. Sazonova, V. A. Kalinkina, S. A. Ulasevich, and M. S. Oshchepkov p. 54  abstract

Development of Potent Antimicrobial Isatin-Sulphonamide Derivatives: In Vitro and In Silico Studies

Samir Panda, Sudhir Kumar Paidesetty, Pronoy Kanti Das, Prasad Sanjay Dhiwar, Biswadeep Dutta, Ankan Jati, Monalisa Mahapatra, Sakshar Saha, and Vishal P. Zambre p. 55  abstract

REVIEW PAPER

Acetate Metabolism in Malignant Tumors

D. A. Korshunov, E. E. Sereda, E. A. Sidenko, G. V. Kakurina, and I. V. Kondakova p. 56  abstract

RESEARCH PAPER

Novel Pyrrole-Based Thiazole Conjugates: Design, Synthesis, Antioxidant, Antidiabetic Assessment, Molecular Docking, Simulation, and In Silico ADME Studies

Bhawana Sati, Anuradha Sharma, Aakash Deep, and Harsh Kumar p. 57  abstract

Design and In Silico Docking-Guided Synthesis of Novel Aromatic Amides with Potential Anti-Inflammatory Activity

Mariam Dawlat Fahmi and Dana Muhammad Hamad Ameen p. 58  abstract

Novel Amide-Based Azetidine Derivatives as Anti-Inflammatory and Antimicrobial Agents: Synthesis, Reaction Optimization, Characterization, and In Silico Pharmacokinetic Properties

P. Pathak, I. J. Modasiya, P. S. Mori, R. Talaviya, and G. G. Dubal p. 59  abstract