Contents

Russian Journal of Bioorganic Chemistry

Vol. 49, No. 2, 2023

Drug Repurposing: An Effective Tool in Modern Drug Discovery

V. S. Kulkarni, V. Alagarsamy, V. R. Solomon, P. A. Jose and S. Murugesan p. 157  abstract

5-Imidazolinone Derivatives as a Potent Pharmacological Agents—A Review

B. Sivakumar and K. Ilango p. 167  abstract

How Conventional Approaches to the Use of Polymer-Containing Composites in Molecular Diagnostics are Changing

D. V. Kapustin p. 180  abstract

Recent Progress of Ubiquitin-Specific-Processing Protease 7 Inhibitors

L. Chi, H. Wang, F. Yu, C. Gao, H. Dai, Xi. Si, L. Liu, Z. Wang, J. Zheng, Y. Ke, H. Liu and Q. Zhang p. 198  abstract

mRNA Vaccine Platform: mRNA Production and Delivery

V. R. Litvinova, A. P. Rudometov, L. I. Karpenko and A. A. Ilyichev p. 220  abstract

A Pharmacological Insight of Piperlongumine, Bioactive Validating Its Therapeutic Efficacy as a Drug to Treat Inflammatory Diseases

M. Zhao, X. Wang, S. A. Kumar, Y. Yao and M. Sun p. 236  abstract

Theoretical Grounding and Formation of Experimental Approaches to Hyaluronidase Structure Consolidation Due to Its Computational Interactions with Shortchain Glycosaminoglycan Ligands

A. V. Maksimenko and R. Sh. Beabealashvili p. 249  abstract

A Systematic Review of Different Classes of Biopolymers and Their Use as Antimicrobial Agents

Jino Affrald R and Shoba Narayan p. 262  abstract

Study on Modification of Paclitaxel and Its Antitumor Preparation

Wenhao Zhou, Hongshang Hu and Ting Wang p. 288  abstract

Hybrid Organomineral Carriers for Therapeutic Proteins

P. V. Zelenikhin, A. G. Galeeva, R. R. Islamova, O. N. Lopatin, R. S. Yarullin and O. N. Ilinskaya p. 298  abstract

Fluorescence Probe Based on Pyrimidine Applied for Rapid Identification of Different Amino Acids

F. Jin and L. Zhao p. 306  abstract

Synthesis of Novel Thiazolidine-4-One Derivatives, Their Cytotoxicity, Antifungal Properties, Molecular Docking and Molecular Dynamics

U. B. Kosurkar, J. Mamilla, T. L. Dadmal, P. C. Choudante, S. N. Mali, S. Misra and R. M. Kumbhare p. 314  abstract

Design, Synthesis, and Study of Anxiolytic Activity of New Pyrrolo[1,2-a]Pyrazine-Containing TSPO Ligands

G. V. Mokrov, A. S. Pantileev, M. A. Yarkova, I. V. Rybina, T. A. Gudasheva, Yu. V. Vakhitova and S. B. Seredenin p. 324  abstract

In vitro Assessment of Anti-Microbial Activity of Aloe vera (Barbadensis miller) Supported through Computational Studies

A. Pandit, A. K. Shukla, Deepika, D. Vaidya, A. Kumari and A. Kumar p. 342  abstract

Effect of Guanidine Derivatives of Quinazoline on the Na+/H+ Exchanger and Intraocular Pressure in Rats

A. S. Taran, L. V. Naumenko, Yu. A. Govorova, N. A. Gurova, A. A. Spasov, A. A. Ozerov and D. V. Merezhkina p. 352  abstract

Synthesis of ZIF-8(Fe) Functionalized with Citral as Potent Antimicrobial Candidate against Multi-Drug Resistant Enteroaggregative Escherichia coli and Non-Typhoidal Salmonella spp.

P. M. Abishad, M. Jayashankar, K. Namratha, B. S. Srinath, N. V. Kurkure, S. B. Barbuddhe, D. B. Rawool, J. Vergis and K. Byrappa p. 360  abstract

Quaternary Ammonium Salt Strategy and Molecular Docking Studies of Novel 5-Acyl-8-(Arylamino)-Quinolines by Acetyl and Methanesulfonyl Chloride for Dual Evaluation Bioactivity

Feng Jin and Xueyong Qi p. 367  abstract

Synthesis, Biological Activity and Crystal Structure Studies of Some Benzoxazepine Derivatives

I. Y. Alja’afreh, I. Al-Shaikh Qasem, A. H. Tarawneh, F. R. Fronczek and M. Ashram p. 376  abstract

Synthesis, Cytotoxicity and In Vitro α-Glucosidase Inhibition of New N-Substituted Glitazone and Rhodanine Derivatives

N. R. Tshiluka, M. V. Bvumbi and S. S. Mnyakeni-Moleele p. 384  abstract

Isolation, Functionalization, In Silico Investigation, and Synthesis of 1,8-Cineole Analog as Antitubercular Agent Targeting InhA

G. Sabarees, S. Gouthaman, V. Alagarsamy, V. Velmurugan and V. Raja Solomon p. 390  abstract

Docking and PASS-Assisted Evaluation of Furaldehyde Substituted Benzimidazoles as Anthelmintic Agents

P. Pattanayak and G. P. Mishra p. 403  abstract

A Route to Synthesize Ionizable Lipid ALC-0315, a Key Component of the mRNA Vaccine Lipid Matrix

I. A. Boldyrev, V. P. Shendrikov, A. G. Vostrova and E. L. Vodovozova p. 412  abstract