Contents

Russian Journal of Bioorganic Chemistry

Vol. 47, No. 2, 2021

Modified Oligonucleotides: New Structures, New Properties, and New Spheres of Application

V. G. Metelev and T. S. Oretskaya p. 339  abstract

Review

Nanoparticles and Nanomotors Modified by Nucleic Acids Aptamers for Targeted Drug Delivery

V. Oravczová, Z. Garaiová and T. Hianik p. 344  abstract

EcoRII Restriction Endonuclease Forms Specific Contacts to the Bases of Its Target Sequence Flipped from DNA in a Transition Complex with Photoactivatable Substrates

O. V. Kirsanova, F. V. Subach, A. G. Loiko, R. I. Eritja and E. S. Gromova p. 367  abstract

Review Article

Targeted Antitumor Drug Delivery to Glioblastoma Multiforme Cells

T. I. Shlapakova, E. E. Tyagunova, R. K. Kostin and D. A. Danilova p. 376  abstract

Synthesis of Novel Representatives of Phosphoryl Guanidine Oligonucleotides

S. A. Zhukov, D. V. Pyshnyi and M. S. Kupryushkin p. 380  abstract

Spiro Benzodiazepine Substituted Fluorocoumarins as Potent Anti-Anxiety Agents

Dayanand Patagar, Akshay Uttarkar, Swarna M. Patra, Jagadish H. Patil, Raviraj Kusanur, Vidya Niranjan and H. G. Ashok Kumar p. 390  abstract

Interaction of Lipophilic Conjugates of Modified siRNAs with Hematopoietic Cells In Vitro and In Vivo

I. V. Chernikov, M. I. Meschaninova, D. V. Gladkikh, A. G. Ven’yaminova, M. A. Zenkova, V. V. Vlassov and E. L. Chernolovskaya p. 399  abstract

Antiviral Activity of Nanocomplexes of Antisense Oligonucleotides Targeting VP72 Protein in Vero Cells Infected by African Swine Fever Virus

A. V. Hakobyan, E. A. Burakova, E. A. Arabyan, A. A. Fokina, A. R. Kotsinyan, S. V. Vasilyeva, O. S. Zakaryan and D. A. Stetsenko p. 411  abstract

A Metabonomics Study of Guan-Xin-Shu-Tong Capsule against Diet-Induced Hyperlipidemia in Rats

X. Gao, Y. Zhang, J. Q. Mu, K. X. Chen, H. F. Zhang and K. S. Bi p. 420  abstract

New Two-Component Pyrene Probes Based on Oligo(2'-O-Methylribonucleotides) for microRNA Detection

O. A. Semikolenova, V. M. Golyshev, B. H. Kim, A. G. Venyaminova and D. S. Novopashina p. 432  abstract

Design and Validation of siRNA Targeting Gankyrin in the Murine Liver

T. A. Prikazchikova, T. O. Abakumova, O. V. Sergeeva and T. S. Zatsepin p. 441  abstract

DNA with a 2-Pyridyldithio Group at the C2' Atom: A Promising Tool for the Crosslinking of the MutS Protein Preserving Its Functional Activity

S. A. Perry, E. A. Kubareva, M. V. Monakhova, R. M. Trikin, E. M. Kosaretskiy, E. A. Romanova, V. G. Metelev, P. Friedhoff and T. S. Oretskaya p. 447  abstract

A Comparative Study of the Hybridization of Phosphoryl Guanidine Oligonucleotides with DNA and RNA

A. A. Lomzov, M. S. Kupryushkin, E. S. Dyudeeva and D. V. Pyshnyi p. 461  abstract

Conjugates of RNase P-Guiding Oligonucleotides with Oligo(N-Methylpyrrole) as Prospective Antibacterial Agents

N. A. Danilin, A. L. Matveev, N. V. Tikunova, A. G. Venyaminova and D. S. Novopashina p. 469  abstract

Detection of Small Products of Transcription from 6S RNA (pRNA) by “Mirror-Like” Northern Blot Hybridization

O. Y. Burenina, T. S. Oretskaya and E. A. Kubareva p. 478  abstract

Norfloxacin Analogues: Drug Likeness, Synthesis, Biological, and Molecular Docking Assessment

Mohammad Arshad, Mohd Shoeb Khan and Shahab A. A. Nami p. 483  abstract

Photoactivatable CRISPR/Cas9 System

E. A. Akhmetova, V. M. Golyshev, I. P. Vokhtantcev, M. I. Meschaninova, A. G. Venyaminova and D. S. Novopashina p. 496  abstract

Problems of the Synthesis of Oligonucleotide Derivatives in the Realization of the Anchimeric Effect

E. S. Dyudeeva, A. S. Pavlova, M. S. Kupryushkin, D. V. Pyshnyi and I. A. Pyshnaya p. 505  abstract

Synthesis and Antiproliferative Activity of Some New Coumarin Derivatives Derived from 8-Hydroxycoumarin

Islam Zaki, El-Sherbiny H. El-Sayed and Eman M. Radwan p. 514  abstract

Synthesis and Bio-Evaluation of N-Benzylpiperidine-8-Hydroxyquinoline Derivatives as Potential Cholinesterase Inhibitors, Metal Ion Chelators and Calcium Channel Blockers

Fan Xiu, Siqi Xu, Chun Zhang and Li Wang p. 524  abstract

Solvent-Free Synthesis, Characterization, and In Vitro Biological Activity Study of Xanthenediones and Acridinediones

Jyoti M. Madar, S. Samundeeswari, Megharaja Holiyachi, Nirmala S. Naik, Varsha Pawar, Parashuram Gudimani, Lokesh A. Shastri, Vijay M. Kumbar and Vinay A. Sunagar p. 535  abstract

Synthesis of New Substituted Diamides. Investigation of Their Antioxidant and Antibacterial Properties

Özgür Yılmaz, Pınar Küce Çevik and Mustafa Kemal Yılmaz p. 543  abstract

Synthesis and Biological Activity Studies of Novel Pyrido[2,3-d]pyrimidines and Pyrido[2,3-d]triazines

Samir Kamel Elsaedany, Mohamed AbdEllatif zein, Elsayed Mohmoud AbdElRehim and Reda Mohammed Keshk p. 552  abstract

An Efficient Synthesis and Reactions of 5-Acetyl-6-Methyl-4-(1,3-Diphenyl-1H-Pyrazol-4-yl)-3,4-Dihydropyrmidin-2(1H)-Thione as Potential Antimicrobial and Anti-Inflammatory Agents

Talaat I. El-Emary, Shawkat A. Abdel-Mohsen and Shereen A. Mohamed p. 561  abstract

Synthesis of Novel Quinoline–Benzoxazolinone Ester Hybrids: In Vitro Anti-Inflammatory Activity and Antibacterial Activity

Sarfaraz F. Shaikh, Pratik P. Dhavan, Pinky R. Singh, S. P. Vaidya, B. L. Jadhav and M. M. V. Ramana p. 572  abstract

Synthesis, Characterization, and Evaluation of Antibacterial Activity of New Bis-Dapsone-Derived Dihydropyridines Using Fe3O4@SiO2–Pr@L-proline

Leila Zare Fekri and Leila Hassan Zadeh p. 584  abstract

Design and Synthesis of 11H-Xantheno[2,1-c][1,2,5]Selenadiazol-11-One Derivatives as Potent Antimicrobial and Antitubercular Agents

Suresh Kuarm Bowroju, Hanumaiah Marumamula and Rajitha Bavanthula p. 593  abstract

Design, Synthesis and Molecular Docking Studies of Novel Indole–Isoxazole–Triazole Conjugates as Potent Antibacterial Agents

M. Prashanthi, H. Ramesh Babu and Janapatla Uma Rani p. 601  abstract