Contents

Russian Journal of Bioorganic Chemistry

Vol. 52, No. 1, 2026

RESEARCH PAPER

Synthesis of New Triazole Compounds: Determination of Antiurease and Antioxidant Activities

T. İ. Gümrükçüoğlu, H. Akgün, B. Bilgin Sökmen, and H. Bektaş p. 01  abstract

One-Pot Piperidine-Catalyzed Synthesis of Oxazolone-Fused 4H-Chromene Scaffolds: Antimicrobial, Antioxidant Potential, Molecular Docking, and ADMET Profiling

V. B. Joshi, M. C. Parmar, I. J. Modasiya, P. K. Patel, R. Pathak, and B. Y. Patel p. 02  abstract

REVIEW PAPER

Applications of Chitin and Chitosan-Based Nanoformulations in Drug Delivery

Khushbu Chandel, Ankur Kapil, Abhishek Pandey, Arnima Sharma, and Bhupendra Singh p. 03  abstract

RESEARCH PAPER

Network Pharmacology, In Silico Computational Chemistry, and Experimental Evidence of the Antiproliferative Effects of Asiatic Acid in Oral Carcinoma Cells

F. Shi, X. Wu, D. Cai, F. Zhang, and Y. Zhang p. 04  abstract

Synthesis, Anticancer and Antibacterial Activity, Molecular Docking, Pharmacokinetic, and DFT Studies of Some New 1,3,4-Thiadiazol Clubbed 1-(Amino(substituted-phenyl)methyl)naphthalen-2-ols

Onkar A. Lotlikar, Siddhesh Jadhav, Sreela Dasgupta, and Shailesh S. Gurav p. 05  abstract

REVIEW PAPER

Evaluation of the Antitubercular Potential of Isoniazid: A Hydrazide Derivative

Thilaga Ganeshmurthy, Rayappan Paustina Ancy, Sanguni Ganesmoorthy, and Maruthapillai Gowri p. 06  abstract

RESEARCH PAPER

CF3-Substituted Benzothiazepines as Promising Anticancer Agents

Jasmin J. Uparkar, Ashwin A. Chalke, and Suresh D. Pawar p. 07  abstract

Synthesis and Biological Evaluation of Novel Naphthoquinone-4-aminosulfonamide Derivatives as Antibacterial Agents

Jiazi Luo, Meishan Li, Yi Wei, Yuban Lei, Haiying Luo, Kelin Lu, Zheng Liu, and Gang Wei p. 08  abstract

Structural Modification of Gefitinib with 1,2,3-Triazole Hybrids and Evaluation of Their Anti-Breast Cancer Activity

Yue Li, Xixi Hou, Qiong Wu, Yajie Guo, Caihong Liu, and En Gao p. 09  abstract

REVIEW PAPER

Synthesis, Properties, and Applications of Aminoquinoline-Derived Schiff Bases and Their Metal Complexes

Sandeep Yadav, Premlata, Sumit Kumar, Aditi Arora, Tanu Gupta, Komal Aggarwal, Pallavi Jain, Rajesh Kumar, and Brajendra K. Singh p. 10  abstract

RESEARCH PAPER

Ursolic Acid-Folic Acid Conjugate in the Treatment of Cervical Cancer

Sham Tambe, Asha Thomas, Prachi Prasad, Mansi Chavan, Pranali Jadhav, Kiran Bharat Lokhande, Akshita Maheshwari, Khushbu Thakre, Sohan Chitlange, and Chandrashekar Raut p. 11  abstract

Exploring the Health Benefits of Pediococcus pentosaceus as a Lactic Acid Bacterium

Amir Hosseinvand and Elena G. Kovaleva p. 12  abstract

One-Pot Synthesis of Pyrazole-Containing 1,2,3-Triazoles: In Vitro and In Silico Antibacterial Activity

Sreenivas Tumu, A. Samba Shiva Rao, V. Geeta, Bhikshapathi Martha, and Jagadeesh Kumar Ega p. 13  abstract

Preliminary Evaluation of Structural Analogs of Honokiol in a Rheumatoid Arthritis Model for the Development of Radioligands for Visualization of Neuroinflammation

K. I. Stosman, K. V. Sivak, D. D. Vaulina, N. B. Viktorov, M. M. Lyubishin, and N. A. Gomzina p. 14  abstract

Bifunctional 1-[4-Methoxy-3-(chloromethyl)]benzaldehyde in the Synthesis of Hybrid Derivatives of 4-Methylquinoline-2-thiol

M. S. Safaryan, N. Z. Hakobyan, R. A. Madoyan, A. G. Sukiasyan, A. S. Grigoryan, M. Yu. Danghyan, A. A. Mnatsakanyan, A. A. Hambardzumyan, and А. A. Harutyunyan p. 15  abstract

Random Mutagenesis-Based Optimization of the Fluorogen-Activating Protein picoFast

D. A. Mustafin, S. A. Krasnova, M. S. Baranov, and Yu. A. Bogdanova p. 16  abstract

Combined Isothermal DNA Amplification Method (HDA–RCA) to Increase Analytical Sensitivity

P. A. Chirkova, S. A. Surzhikov, I. V. Grechishnikova, A. V. Chudinov, and S. A. Lapa p. 17  abstract

Analogues of the Antibiotic Chloramphenicol. Synthesis, Docking, and Biological Properties of Products of N- and O-Acetylation of (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol (D-(–)threoamine)

N. Z. Hakobyan, R. A. Madoyan, A. G. Sukiasyan, H. A. Sargsyan, J. L. Barseghyan, M. Yu. Danghyan, H. A. Panosyan, A. S. Sargsyan, A. A. Hambardzumyan, A. A. Hovhannisyan, A. S. Harutyunyan, and A. A. Harutyunyan p. 18  abstract

Effect of Synthetic Peptide LKEKK in Experimental Myocardial Infarction

E. V. Navolotskaya, D. V. Zinchenko, A. A. Kolobov, Yu. A. Zolotarev, and A. N. Murashev p. 19  abstract

A New Approach to the Synthesis of Sydnonimines Carboxyethylated at the Exocyclic Nitrogen Atom

D. S. Ivanov, S. A. Krasnova, V. Yu. Balaban’yan, N. S. Popov, I. N. Myasnyanko, and M. S. Baranov p. 20  abstract

Synthesis and Antioxidant Activity of Dihydroquinopimaric Alcohol Acylates

E. V. Tretyakova, T. A. Sapozhnikova, S. F. Gabdrakhmanova, and O. B. Kazakova p. 21  abstract

Detection of B-Cell Epitopes of Hepatitis C Virus Envelope Proteins Associated with Viral Elimination

M. D. Stuchinskaya, L. I. Nikolaeva, A. N. Belyavtsev, N. G. Shevchenko, V. V. Kupriyanov, and N. S. Shastina p. 22  abstract

Synthesis and Study of the Optical Properties of a New Green Fluorescent Protein Chromophore Analogue with an sp-Hybridized Carbon Fragment

S. A. Krasnova, A. A. Mikhaylov, and M. S. Baranov p. 23  abstract

Composite Aerogel Materials with Hemostatic Effect Based on Alginate and Chitosan

N. A. Gorshkova, O. S. Brovko, and S. L. Kashutin p. 24  abstract

LbCas12a Nuclease Exhibits Nonspecific 3′→5′ Exonuclease Activity In Vitro

A. V. Chirinskaite, P. S. Luganskaya, O. A. Kirillov, I. I. Akhmarov, D. A. Kandina, E. A. Andreeva, J. V. Sopova, and E. I. Leonova p. 25  abstract

Design, Synthesis, In Vitro Hydrolysis and Biological Evaluation of Antioxidant-Conjugated Mutual Prodrugs of Naproxen

Rajat Goyal, Sumeet Gupta, Prabodh Chander Sharma, and Hitesh Chopra p. 26  abstract