Contents

Russian Journal of Bioorganic Chemistry

Vol. 51, No. 1, 2025

REVIEW PAPER

Multifunctional Roles and Phytopharmacological Potential of Ursolic Acid: an Invaluable Natural Nutraceutical Agent

Pranay Wal, Shubhi Kaushal, Jyotsana Dwivedi, Pallavi Patel, Pranjal Sachan, and Pooja Srivastava p. 1  abstract

Hydrazide-Hydrazone Derivatives and Their Antitubercular Activity

B. R. Thorat, S. N. Mali, Umang Shah, A. Garg, R. Agrawal, S. A. Arvindekar, J. N. Cruz, M. Santana de Oliveira, A. B. Shaik, and B. V. S. Lokesh p. 35  abstract

RESEARCH PAPER

A Quantum-Mechanical Method Reveals the Potential Basis of Antioxidant Activities of Phytomolecules from Jasminum Species: Isolation, Spectral Characterization, DFT, and In Vitro Studies

Arun Mittal, Suraj N. Mali, Anima Pandey, A. Kuznetsov, and Satish Sardana p. 53  abstract

Design, Synthesis, and Molecular Docking of Novel Benzothiazinone Derivatives as DprE1 Inhibitors with Potential Antitubercular Activities

M. S. Raghu, Amar Yasser Jassim, K. Yogesh Kumar, Fahd Alharethy, M. K. Prashanth, and Byong-Hun Jeon p. 65  abstract

Antitumor Mechanisms of Olive Fruit Metabolites, Maslinic, and Oleanolic Acids on Lung Cancer Cells

Canan Afacan, Isik Didem Karagoz, and Ahmet Cakir p. 79  abstract

REVIEW PAPER

Recent Advances in Liposomes Efficacy as a Drug Delivery Platform for Melanoma Treatment

Elham Zarenezhad, Zahra Kazeminejad, Mahsa Rostami Chijan, Mahmoud Osanloo, Ensieh Nournia, Abdolmajid Ghasemian, and Mahrokh Marzi p. 93  abstract

RESEARCH PAPER

Synthesis and Study of the Hepatoprotective Activity of New Uracil Derivatives

Yu. Z. Khazimullina, A. R. Gimadieva, V. R. Khairullina, E. R. Kudoyarov, D. O. Karimov, and A. G. Mustafin p. 117  abstract

Nano-frFAST: Design of a New Genetically-Encoded Far-Red Fluorescent Label

E. L. Sokolinskaya, Yu. A. Bogdanova, I. N. Myasnyanko, A. I. Sokolov, S. A. Krasnova, and M. S. Baranov p. 128  abstract

Comparison of Methods for Rapid Determination of Cholesterol Concentration in Human Sperm Membrane in Clinical Laboratory Practice

A. G. Mironova, S. I. Afanasyeva, A. V. Sybachin, V. V. Spiridonov, M. A. Bolshakov, and E. Yu. Simonenko p. 137  abstract

Arylidene-Imidazolones with Three Electron-Donating Substituents as Fluorogenic Dyes for Lipid Droplets of Living Cells

D. I. Rudik, A. R. Gil’vanov, A. Yu. Smirnov, Yu. A. Bogdanova, S. A. Krasnova, and M. S. Baranov p. 145  abstract

Synthesis and Antimicrobial Evaluation of (E)-2-(4-((4-((1-(2,4-Dichlorophenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)methyl)-2-methoxyphenoxy)methyl)-1H-1,2,3-triazol-1-yl)-N-phenylacetamide Derivatives

Cheryl T. Mascarenhas, Jaidip B. Wable, Hemantkumar N. Akolkar, Nirmala R. Darekar, and Pradnya J. Prabhu p. 151  abstract

Analysis of the Content of Membrane Lipids of Mytilid Bivalve Mollusks and Strongylocentrotid Sea Urchins with Different Lifespans

A. L. Drozdov, T. V. Sikorskaya, and V. P. Grigorchuk p. 160  abstract

REVIEW PAPER

Exploring the Anticancer Properties of β-Sitosterol

Sainath Bhavsar, Sunita Pachori, and Jitendra Patil p. 171  abstract

RESEARCH PAPER

Thiazolidine Based Quinazoline Hybrids: Synthesis, Docking, DFT, Molecular Dynamic Study, and In Vitro Antidiabetic Evaluation

S. Gharge, S. G. Alegaon, S. D. Ranade, and R. S. Kavalapure p. 177  abstract

Preparation of Boron-Containing S-Nitrosothiol Based on Homocysteinylamides of Human Serum Albumin for Combined NO-Chemical and Boron-Neutron-Capture Therapy

T. V. Popova, M. Van, T. N. Kurochkin, S. A. Tsyrempilov, O. D. Zakharova, V. N. Silnikov, and T. S. Godovikova p. 202  abstract

Spectral-Luminescent Properties of Products of Interaction of Polyfluorinated Pyrazoline-Containing Pyrylium Dyes with Bovine Serum Albumin and Amino Acids

V. V. Shelkovnikov, D. D. Doroshenko, I. Yu. Kargapolova, P. A. Kozlakov, N. A. Shestakov, and Yu. S. Sotnikova p. 216  abstract

Visualization of H3K9me3 in Embryoid Bodies Using Genetically Encoded Fluorescent Sensor MPP8-Green

A. I. Stepanov, E. B. Zhigmitova, E. B. Dashinimaev, A. A. Galiakberova, L. V. Putlyaeva, K. A. Lukyanov, and N. G. Gurskaya p. 229  abstract

Characterization of Combined Effects of Reactive Oxygen Metabolites, Complement System, and Antimicrobial Peptides In Vitro

I. A. Krenev, E. V. Egorova, N. P. Gorbunov, V. A. Kostevich, A. V. Sokolov, A. S. Komlev, Y. A. Zabrodskaya, O. V. Shamova, and M. N. Berlov p. 235  abstract

MINI-REVIEW PAPER

A Mini-Review on Pyridine—A Versatile Compound in the Field of Therapeutic Agents

Shivani Kapletiya, Harsh Mehta, and Sabirkhan Pathan p. 251  abstract

RESEARCH PAPER

Accessible Synthesis Methods and Physicochemical Properties of Quinoline-Derived Schiff Bases

L. P. Hambardzumyan, and I. L. Aleqsanyan p. 266  abstract

Quantitative Analysis of Biomolecular Condensates on a Modified Support

A. S. Shtork, Iu. I. Pavlova, J. I. Svetlova, M. S. Iudin, E. N. Grafskaia, V. A. Manuvera, S. E. Alieva, A. M. Varizhuk, V. N. Lazarev, and T. S. Vedekhina p. 273  abstract

Chemical Synthesis of Novel DDR1 Inhibitors and Their Activity Against Gefitinib-Resistant Non-Small Cell Lung Cancer

Xuemei Xu, Siyu Chen, Doudou Sun, Xuebao Wang, and Zhouyang Xu p. 285  abstract

A New Green and Efficient Method for Pyranopyrazoles Synthesis in a Single Pot Using Multiple Components, In Silico Pharmacokinetics with Cytotoxic Assessments

N. N. Jha, B. R. Thorat, S. N. Mali, S. A. Tawade, Umang Shah, and R. S. Yamgar p. 298  abstract

Construct Design, Isolation, and Purification of the Human GPR17 Receptor Monomeric Form for Structural and Functional Studies

N. A. Safronova, A. P. Luginina, A. A. Sadova, M. B. Shevtsov, O. V. Moiseeva, V. I. Borshchevskiy, and A. V. Mishin p. 308  abstract

Live-Cell Visualization of Histone Modification Using Bimolecular Complementation

A. I. Stepanov, L. V. Putlyaeva, A. A. Shuvaeva, M. A. Andrushkin, M. S. Baranov, N. G. Gurskaya, and K. A. Lukyanov p. 320  abstract

Synthesis, Characterization, and Exploring the Antibacterial and Antifungal Potential of 1,4-Dihydropyrimido[1,2-a]benzimidazole Derivatives

Dharmesh Katariya, Kailash Pancholi, and Mahendra Borisagar p. 330  abstract

DHPMs C5 Amide Bearing Benzothiazole Moiety Inhibit AChE: Design, Synthesis, In Vitro and In Silico Studies

Pardis Samiei, Dara Dastan, and Ahmad Ebadi p. 340  abstract

Chemotherapeutic Boron-Containing Homocysteinamides of Human Serum Albumin

M. Wang, S. A. Tsyrempilov, I. A. Moskalev, O. D. Zakharova, A. I. Kasatova, V. N. Sil’nikov, T. S. Godovikova, and T. V. Popova p. 354  abstract