Contents

Neurochemical Journal

Vol. 19, No. 4, 2025

Introduction by the Editor-in-Chief

N. V. Gulyaeva p. 517  abstract

REVIEW ARTICLES

I.P. Ashmarin and His Contribution to the Development of Biochemistry at Leningrad (St. Petersburg) State University

N. D. Eshchenko and O. V. Galkina p. 518  abstract

I.P. Ashmarin and the Study of Neurotropic Activity of Regulatory Peptides

N. G. Levitskaya, N. Yu. Sarycheva, O. G. Voskresenskaya, and V. A. Dubynin p. 525  abstract

Regulation of Primary Hemostasis by Peptides with Neuroprotective Effect

L. A. Lyapina, M. E. Grigorjeva, T. A. Shubina, T. Yu. Obergan, and N. F. Myasoedov p. 537  abstract

Neuropeptide Cyclo-Prolylglycine: Discovery, Pharmacological Effects, and Mechanism of Action

T. A. Gudasheva, K. N. Koliasnikova, A. G. Alyaeva, and P. Yu. Povarnina p. 549  abstract

Peptide HLDF-6 Exhibits Neuroprotective Activity in Neurodegenerative Diseases

Yu. A. Zolotarev and A. K. Dadayan p. 557  abstract

Anorexigenic and Neuromodulatory Functions of Guanylins

E. D. Snigireva, N. S. Sirotina, and O. V. Smirnova p. 570  abstract

Proteins as Candidates for the Neurodegeneration Biomarkers

I. S. Boksha, T. A. Prokhorova, O. K. Savushkina, E. B. Tereshkina, E. A. Vorobyeva, and G. Sh. Burbaeva p. 579  abstract

Nociceptin and Stress: A Review of 30 Years of Experimental Research

I. Yu. Shamakina, V. S. Kokhan, F. Sh. Shagiakhmetov, and N. Yu. Sarycheva p. 592  abstract

The Effect of Hypoxia on the Antioxidant System Formation of the Developing Brain

L. I. Klys, O. V. Galkina, O. V. Vetrovoy, and N. D. Eschenko p. 602  abstract

Changes in the Expression of Purinergic Receptors of the CNS Cells During Cerebral Ischemia

I. G. Savinkova, I. I. Babkina, M. P. Morozova, and L. R. Gorbacheva p. 611  abstract

Gasotransmitters (NO, H2S, CO) as Contributors to the Nociceptive Process in the Trigeminovascular System

S. O. Svitko, A. S. Ananev, E. S. Nevsky, K. S. Shaidullova, and G. F. Sitdikova p. 621  abstract

Sympathetic Regulation of Homeostatic Plasticity at the Cholinergic Neuromuscular Junction

E. A. Bukharaeva and A. M. Petrov p. 638  abstract

Induced Pluripotent Stem Cells: A Unique Model for Studying the Human Brain in Health and Disease

E. V. Novosadova and I. A. Grivennikov p. 646  abstract

The Role of Ion Channels in the Development of the Nervous System

A. D. Okhalnikov, J. M. Kovriga, V. S. Tarabykin, and M. S. Gavrish p. 664  abstract

EXPERIMENTAL ARTICLES

Physiological Effects of Modified Obestatin Analogues in Rats

A. S. Maklakova, M. V. Maslova, and A. V. Graf p. 674  abstract

Leptin Reception in the Ventromedial Nucleus of the Hypothalamus in the Aging Rats

P. M. Masliukov, L. G. Pankrasheva, A. A. Spirichev, P. A. Anfimova, and A. F. Budnik p. 685  abstract

Synthesis and Study of Effects of the Arginine-Vasopressin Fragment (6-9) Analog on Rat Behavior in the “Social Behavior” Experiment

K. U. Baradzina, A. A. Stakhanova, L. I. Kviatkouskaya, V. P. Martinovich, O. G. Voskresenskaya, and O. V. Gribovskaya p. 692  abstract

The Role of Neuropeptide CGRP in the Regulation of Neurotransmitter Release in Regenerating Mouse Neuromuscular Junctions

P. O. Bogacheva, E. O. Tarasova, and O. P. Balezina p. 700  abstract

Peptide ACTH(6-9)-PGP Attenuates the Consequences of Chronic Unpredictable Stress in Male Rats

O. V. Dolotov, K. A. Yatsenko, L. A. Andreeva, N. F. Myasoedov, and I. A. Grivennikov p. 710  abstract

PAR1-Mediated Retrograde Action of Brain-Derived Neurotrophic Factor and Its Prodomain in Mature Mouse Motor Synapses is Provided by Furin Activity

A. I. Molchanova, E. I. Shepelev, and A. E. Gaydukov p. 717  abstract

PAPP-A-Mediated Proteolytic Cleavage of IGFBP-4 and Age-Related Changes in the Primary Culture of Rat Astrocytes

D. A. Gushchevarov, I. M. Ermakov, P. N. Datskevich, F. N. Rozov, V. L. Filatov, A. B. Postnikov, and D. V. Serebryanaya p. 728  abstract

Combined Action of Benzodiazepine Tranquilizers and Peptide Anxiolytic Selank in BALB/с Mice

N. V. Kost, O. Yu. Sokolov, S. A. Zozulya, and N. F. Myasoedov p. 743  abstract

Effect of the Microbiota Metabolite Butyric Acid on Behavior, Neuroinflammation, and Oxidative Stress Level in a Mouse Model of Dysbiosis

A. F. Salikhzyanova, A. I. Mullakaeva, I. F. Shaidullov, G. F. Sitdikova, and O. V. Yakovleva p. 749  abstract

The Effect of Periodic Hypoxia on the Behavior and Parameters of the Antioxidant System in Male Rats of Different Ages

S. D. Simonenko, O. I. Patiavina, I. A. Kabiolskiy, O. K. Savushkina, E. B. Tereshkina, T. A. Prokhorova, E. A. Sebentsova, and N. G. Levitskaya p. 760  abstract

The Effect of Repeated Argon Inhalations on the Behavior of Wistar Rats in a Neonatal Hypoxia Model

I. A. Kabiolskiy, A. S. Degtyar, P. D. Panasenkov, A. V. Loboda, S. V. Potapov, N. Yu. Sarycheva, and V. A. Dubynin p. 771  abstract

Disruption of Blood Flow Autoregulation in the Middle Cerebral Artery Bed in Rats with Carotid Artery Stenosis

K. A. Bogotskoy, A. S. Borovik, A. A. Borzykh, A. A. Druzhinina, M. G. Pechkova, and O. S. Tarasova p. 782  abstract

Effect of Gestational Diabetes in Female Rats on Brain Astrocyte Functions in Their Offspring

I. I. Babkina, I. G. Savinkova, A. S. Artyukhov, and L. R. Gorbacheva p. 791  abstract

The Effect of Trehalose on Autophagy Gene Transcription and Ultrastructure in Neurons and Glia of 5-Month-Old db/db Mice, a Model of Type 2 Diabetes-Associated Neurodegeneration

T. A. Korolenko, A. B. Pupyshev, V. M. Belichenko, N. P. Bgatova, M. V. Tenditnik, L. A. Fedoseeva, N. V. Goncharova, M. V. Ovsyukova, E. T. Korolenko, E. L. Zavjalov, and M. A. Tikhonova p. 800  abstract

Increased Density of D2-like, but Not D1-like, Dopamine Receptors in the Caudal Dorsal Striatum of Rats with Different Forms of Generalized Epilepsy

E. T. Tsyba, S. M. Kuzhughet, L. M. Birioukova, I. S. Midzyanovskaya, and K. R. Abbasova p. 809  abstract

Temporal Dynamics of Neuroinflammation after Cortical Injury in Mice

I. V. Manzhulo, A. A. Tyrtyshnaia, F. K. Avgustinovich, O. S. Manzhulo, E. S. Gromova, and D. N. Ivashkevich p. 819  abstract

Analysis of Changes in Parameters of Neuromuscular Synaptic Transmission in Mice During Early Postnatal Ontogeny

E. S. Nevsky, K. A. Petrov, D. V. Samigullin, and A. I. Malomouzh p. 829  abstract

СLINICAL NEUROCHEMISTRY

The Evaluation of Serum Levels of Matrix Metalloproteinases in the Acute Period after Ischemic Stroke

K. S. Kucherova, E. S. Koroleva, V. M. Alifirova, N. G. Brazovskaya, L. A. Levchuk, and S. A. Ivanova p. 837  abstract

SHORT COMMUNICATIONS

Snake α-Neurotoxins with Different Affinity to Two Binding Sites of Muscle-Type Nicotinic Acetylcholine Receptors

E. V. Kryukova, V. I. Tsetlin, and Yu. N. Utkin p. 844  abstract

REVIEW ARTICLES

The Midbrain Dopaminergic System in Behavioral Models of Depression

N. Yu. Ivlieva p. 848  abstract

EXPERIMENTAL ARTICLES

Analysis of the Relationship between the Concentration of Neurotransmitters and Tau Protein in the Brain of Animals with Chronic Traumatic Encephalopathy

D. I. Pozdnyakov, O. V. Kharitonova, D. R. Burzhumova, and M. P. Efremova p. 858  abstract

The Brain Lactate Dehydrogenase of Little Ground Squirrels (Spermophilus pygmaeus Pall.) during Hibernation and Arousal

R. A. Khalilov, A. M. Dzhafarova, V. R. Abdullaev, and N. K. Klichkhanov p. 863  abstract

Effect of NMDA Receptor Blocker Hemantane in Combination with TRPV1 Agonist Capsaicin on Pain Response in Mice

E. A. Ivanova, A. G. Vasilchuk, and T. A. Voronina p. 875  abstract

Evaluation of Expression of a New Isoform djGDNF47 in Neural Cells

V. V. Parshina, D. V. Shamadykova, V. A. Kolesnikova, L. V. Fab, A. V. Revishchin, and G. V. Pavlova p. 881  abstract

Neurochemical Analysis of the Effect of the Combination of Ladasten with Fabomotizole on the Dopaminergic System of the Mouse Brain in 6-Hydroxydophamine Model of Parkinsonian Syndrome

V. E. Marievskii, I. A. Lubanskii, L. F. Zainullina, and V. L. Dorofeev p. 891  abstract

Effects of Prenatal Hyperhomocysteinemia on Autophagy and mTOR Signaling in the Developing Rat Brain

A. V. Mikhel, D. S. Vasilev, A. V. Gorbova, Yu. P. Milyutina, I. V. Zalozniaia, N. L. Tumanova, and A. V. Arutjunyan p. 902  abstract

Colony Stimulating Factor 1 Receptor/c-Myc Axis Promotes Microglial M2 Polarization to Augment Proliferation of Glioma Cells

F. Fu, C. H. Du, Q. Chen, and L. Tian p. 916  abstract

Integrating the Multiscale Molecular Modelling Techniques in Identification of Rat-TTBK1 Inhibitors from Glycyrrhiza glabra Plant: Homology-Modelling, Docking, MD Simulation, PCA Analysis, Cluster Analysis and MMGB/SA Study

Mansi Verma, Niraj Kumar Singh, and Mohd Usman Mohd Siddique p. 926  abstract

Stimulation of TRPM2 Channel in Glioblastoma Tumour Cells by Gallic Acid Potentiated the Anti-Tumour and Oxidant Effects of Doxorubicin

Yener Yazğan, Betül Yazğan, and Adem Ahlatcı p. 942  abstract

CLINICAL NEUROCHEMISTRY

Association Analysis of Some Polymorphic Variants of Dopaminergic Network Genes (DRD2 rs1800497, DRD4 rs1800955, CNTF rs1800169) with Dopamine and CNTF Levels in Patients with Vibration Disease

G. M. Bodienkova, N. P. Chistova, E. V. Boklazhenko, and O. L. Lakhman p. 954  abstract

Analysis of Associations of Temperament Traits with Prolactin Levels in Sakha (Yakut) Men Subjected to Stress in Childhood

S. S. Nakhodkin, A. V. Kazantseva, N. A. Barashkov, V. G. Pshennikova, S. S. Kuzmina, E. K. Khusnutdinova, and S. A. Fedorova p. 960  abstract