Vol. 15, No. 4, 2021

Neurochemical Journal

Problems with Technologies of Genomic Editing and Transgenesis

A. P. Bolshakov p. 333 abstract

Genome Editing Technology for the Study and Correction of Neurodegenerative Diseases

I. A. Grivennikov and V. Z. Tarantul p. 339 abstract

Creation and Research of Cell Models of Hereditary Neurodegenerative Diseases Using Directed Genome Editing

S. P. Medvedev, T. B. Malankhanova, K. R. Valetdinova and S. M. Zakian p. 353 abstract

Editing the Epigenome in Neurodegenerative Diseases

A. S. Vetchinova, E. Yu. Fedotova and S. N. Illarioshkin p. 359 abstract

Using Genome Editing for Alzheimer’s Disease Therapy: from Experiment to Clinic

M. Yu. Stepanichev p. 367 abstract

SLC6A1 and Neuropsychiatric Diseases: The Role of Mutations and Prospects for Treatment with Genome Editing Systems

E. S. Bukina, N. V. Kondratyev, S. V. Kozin, V. E. Golimbet, A. S. Artyuhov and E. B. Dashinimaev p. 376 abstract

CRISPR-Cas9 Delivery with the Ribonucleoprotein Complexes Increased EGFP Editing Efficiency

Ya. S. Slesarenko, A. G. Bykonya, A. A. Anuchina, M. I. Zaynitdinova, N. A. Evtushenko, A. V. Lavrov and S. A. Smirnikhina p. 390 abstract

Generation of TNFαR1 and ASIC1a Knockout Human Neural Stem Cells In Vitro by CRISPR/Cas9 System

A. S. Poltavets, N. V. Mescheryakova, Yu. S. Kolesova, A. S. Artyuhov and E. B. Dashinimaev p. 398 abstract

Toxic Damage to Motor Neurons

M. N. Zakharova, I. S. Bakulin and A. A. Abramova p. 410 abstract

Learning Difficulties and Oxidative Stress in Autism Spectrum Disorder: A Review of the Role of Nutritional Interventions

Maryam Turkestani, Norah Aldosiry, Najat Hamed, Ramesa Shafi Bhat and Afaf El-Ansary p. 422 abstract

Neurotropic Viruses as a Tool for Neural Circuit-Tracing

Fan Zhang, Li-bin Wu, Qing Yu, Min-jun Wang, Xue-ling Zeng, Xiao-tong Wei, Zi-jian Wu, Rong-lin Cai and Ling Hu p. 435 abstract

Neurochemical and Behavioral Effects of Alpha-Synuclein Oligomers in Three-Month-Old Mice

V. V. Sherstnev, M. A. Gruden’, O. A. Solov’eva, V. S. Kudrin, V. B. Narkevich, N. P. Mikhailova and A. M. Ratmirov p. 448 abstract

Intrathecal Infusion of Diosgenin during the Chronic Phase of Spinal Cord Injury Ameliorates Motor Function and Axonal Density

Aoi Nakano, Ximeng Yang, Tomoharu Kuboyama, Yuna Inada and Chihiro Tohda p. 454 abstract

U73122 and m-3M3FBS Regulate the GABAergic Neuron Regeneration via PLCβ in Planarian Dugesia japonica

Hui Zhen, Mingyue Zheng, Qian Song, Hongjin Liu, Zuoqing Yuan, Zhonghong Cao and Bosheng Zhao p. 462 abstract

Genotype–Phenotype Correlation of Novel NF1 Gene Variants Detected by NGS in Patients with Neurofibromatosis Type 1

Ozlem Oz p. 469 abstract

The Relationship of Antidepressant Therapy with Neuroinflammatory Changes and Inflammatory Response in Major Depressive Disorder

S. Korkut and S. Kulaksizoglu p. 477 abstract

Comparative Assessment of Neurochemical Indices in Patients with Occupational Pathology Caused by Physical and Chemical Factors

G. M. Bodienkova and E. V. Boklazhenko p. 482 abstract