Contents

Molecular Biology

Vol. 54, No. 6, 2020

Reviews

Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions

E. N. Proshkina, I. A. Solovev, M. V. Shaposhnikov and A. A. Moskalev p. 777  abstract

The Challenges of Vaccine Development against Betacoronaviruses: Antibody Dependent Enhancement and Sendai Virus as a Possible Vaccine Vector

T. A. Zaichuk, Y. D. Nechipurenko, A. A. Adzhubey, S. B. Onikienko, V. A. Chereshnev, S. S. Zainutdinov, G. V. Kochneva, S. V. Netesov and O. V. Matveeva p. 812  abstract

Cell Replacement Therapy in Parkinson’s Disease—History of Development and Prospects for Use in Clinical Practice

N. V. Katolikova, A. B. Malashicheva and R. R. Gainetdinov p. 827  abstract

Hypertrophic Cardiomyopathy as an Oligogenic Disease: Transcriptomic Arguments

N. M. Baulina, I. S. Kiselev, O. S. Chumakova and O. O. Favorova p. 840  abstract

Genomics. Transcriptomics

Increasing the Uniformity of Genome Fragment Coverage for High-Throughput Sequencing of Influenza A Virus

Y. V. Mikhaylova, A. A. Shelenkov, Y. G. Yanushevich and D. A. Shagin p. 851  abstract

Exon and Intron Variability in Salmonidae Growth Hormone Genes

D. N. Kamenskaya, M. V. Pankova and V. A. Brykov p. 857  abstract

The Effect of I155T, K156Q, K156E and N186K Mutations in Hemagglutinin on the Virulence and Reproduction of Influenza A/H5N1 Viruses

T. A. Timofeeva, G. K. Sadykova, N. F. Lomakina, A. S. Gambaryan, I. A. Rudneva, E. B. Timofeeva, A. A. Shilov, E. Y. Boravleva, M. M. Zhuravleva, P. A. Ivanov, E. L. Ryazanova and A. G. Prilipov p. 861  abstract

Novel miRNAs as Potential Regulators of PD-1/PD-L1 Immune Checkpoint, and Prognostic Value of MIR9-1 and MIR124-2 Methylation in Ovarian Cancer

N. E. Kushlinskii, V. I. Loginov, D. O. Utkin, E. A. Filippova, A. M. Burdennyy, E. A. Korotkova, I. V. Pronina, S. S. Lukina, A. V. Smirnova, E. S. Gershtein and E. A. Braga p. 870  abstract

Phylogeography and Mitochondrial Polymorphism of Asian Coho Salmon

D. A. Zelenina, V. A. Soshnina and A. A. Sergeev p. 876  abstract

Molecular Cell Biology

shRNA-Mediated Suppression of γ-Synuclein Leading to Downregulation of p38/ERK/JNK Phosphorylation and Cell Cycle Arrest in Endometrial Cancer Cells

D. Sun, W.-Y. Li, S.-H. Chen, Z.-F. Zhi, H.-S. Lin, J.-T. Fan and Y.-J. Fan p. 884  abstract

Effects of the Hydrogen Sulfide Donor GYY4137 and HSP70 Protein on the Activation of SH-SY5Y Cells by Lipopolysaccharide

M. M. Yurinskaya, D. G. Garbuz, V. N. Afanasiev, M. B. Evgen’ev and M. G. Vinokurov p. 894  abstract

Direct Molecular Fishing of Zinc-Dependent Protein Partners of Amyloid-beta 1–16 with the Taiwan (D7H) Mutation and Phosphorylated Ser8 Residue

P. V. Ershov, Yu. V. Mezentsev, E. O. Yablokov, L. A. Kaluzgskiy, A. S. Ivanov, N. V. Gnuchev, V. A. Mitkevich, A. A. Makarov and S. A. Kozin p. 904  abstract

Methods

Extraction and Separation of Sinapine from Rapeseed Cake and the Mode of Action of Melanin Production Inhibition

Z. T. Yang, D. X. Lu, E.-K. Hong, B. Y. Zhang, M. C. Jiang, Y. J. Yang and D. J. Zhang p. 911  abstract

Microarray for Quantitative Determination of Inflammatory Biomarkers in a Culture Medium

S. A. Voloshin, G. U. Feyzkhanova, E. N. Savvateeva, O. V. Smoldovskaya and A. Yu. Rubina p. 919  abstract