Contents

Molecular Biology


Vol. 57, No. 5, 2023


Reviews

Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis

N. A. Lunina, D. R. Safina and S. V. Kostrov p. 765  abstract

Digital PCR as a Highly Sensitive Diagnostic Tool: A Review

K. V. Kopylova, Ed. W. Kasparov, I. V. Marchenko and M. V. Smolnikova p. 793  abstract

The Role of the WGR Domain in the Functions of PARP1 and PARP2

N. V. Maluchenko, A. N. Korovina, A. A. Saulina, V. M. Studitsky and A. V. Feofanov p. 802  abstract


Genomics. Transcriptomics

A Comparative Analysis of Mitochondrial Genome Mutation Spectra in Human Populations

B. A. Malyarchuk p. 811  abstract

Analysis of the Complete Tomato Aspermy Virus Genomes Suggests Reassortment in Russian Isolates from Chrysanthemum

A. A. Sheveleva, G. S. Krasnov, A. V. Kudryavtseva, A. V. Snezhkina, E. V. Bulavkina and S. N. Chirkov p. 816  abstract

Efficiency of Escherichia coli and Bacillus subtilis Expression Systems for Production of Binase Mutants

A. I. Nadyrova, A. S. Kosnyrev, V. V. Ulyanova, E. V. Dudkina, V. I. Vershinina and O. N. Ilinskaya p. 825  abstract

DNA Methylation Profile of CD14+ Monocytes Changes in Primary Progressive Multiple Sclerosis

I. S. Kiselev, O. G. Kulakova, O. A. Baturina, M. R. Kabilov, A. N. Boyko and O. O. Favorova p. 836  abstract

Association of Polymorphic Genome Variants in the 2q32.1 Locus with the Development of Vasovagal Syncope

N. A. Matveeva, B. V. Titov, E. A. Bazyleva, E. A. Kuchinskaya, M. S. Kozin, A. V. Favorov, A. V. Pevzner and O. O. Favorova p. 843  abstract


Cell Molecular Biology

Drosophila melanogaster Lifespan Is Regulated by nejire Gene Expression in Peripheral Tissues and Nervous System

L. A. Koval, E. N. Proshkina, N. V. Zemskaya, I. A. Solovev, E. V. Schegoleva, M. V. Shaposhnikov and A. A. Moskalev p. 848  abstract

The Mechanism of Bimodal Effect of DL-Butyonine Sulfoximine on Constitutive Androstane and Pregnane X Receptors In Vitro

Y. V. Abalenikhina, A. V. Shchulkin, A. A. Seidkulieva, E. D. Rokunov, F. T. Gadzhieva and E. N. Yakusheva p. 867  abstract

Hepatitis C Virus Nonstructural Protein 3 Increases Secretion of Interleukin-1beta in HEK293T Cells with a Reconstructed NLRP3 Inflammasome

A. A. Latanova, K. K. Tuchinskaya, E. S. Starodubova and V. L. Karpov p. 876  abstract

Changes in the Activities and Contents of Individual Forms of Proteasomes in Samples of the Cerebral Cortex during Pathology Development in 5xFAD Mice

A. V. Morozov, A. V. Burov, S. Yu. Funikov, E. V. Teterina, T. M. Astakhova, P. A. Erokhov, A. A. Ustyugov and V. L. Karpov p. 885  abstract

Dynamic Changes in the Activities and Contents of Particular Proteasome Forms in the Cerebral Cortex of C57BL/6 Mice during Aging

A. V. Burov, S. Yu. Funikov, T. M. Astakhova, E. V. Teterina, V. O. Nebogatikov, P. A. Erokhov, A. A. Ustyugov, V. L. Karpov and A. V. Morozov p. 897  abstract


Bioinformatics

Spatial Models of Piezo Proteins and Protein‒Protein Interaction Networks in Trichoplax Animals (Placozoa)

A. V. Kuznetsov, I. Yu. Grishin and D. N. Vtyurina p. 905  abstract


Methods

Latex Agglutination as an Alternative to the Hemagglutination Reaction of Influenza Viruses

P. A. Ivanov, A. V. Lyashko, S. A. Ionov, D. N. Shcherbinin, I. A. Rudneva, A. A. Shilov, N. I. Bunkova, M. M. Shmarov and T. A. Timofeeva p. 913  abstract