Contents

Molecular Biology

Vol. 60, No. 3, 2026

REVIEWS

Modern Methods of Molecular Modeling of Aptamers

N. O. Kudryashova, V. A. Dolgusheva, I. V. Dobrokhotov, Sh. Sh. Nasayev, and A. A. Moskalev p. 329  abstract

Omnipresent Lactate: Normalization of the Tumor Microenvironment as a Prerequisite for Any Anticancer Therapy

K. S. Vishnyakova, X. Pan, and Y. E. Yegorov p. 343  abstract

DNA Methylation as a Biomarker for Chromatinopathies: Present and Future

O. A. Zemlianaia, A. V. Efremova, V. V. Strelnikov, and D. V. Zaletaev p. 365  abstract

Yeast as a Biochemical Model for Diseases Associated with Impaired Intracellular Proteolytic Systems

A. O. Sosnovtseva, E. S. Starodubova, D. S. Karpov, and V. L. Karpov p. 376  abstract

WRN and Other RecQ Helicases in Life Cycles of Viruses

O. E. Shchigal, S. P. Korolev, A. N. Anisenko, and M. B. Gottikh p. 383  abstract

GENOMICS. TRANSCRIPTOMICS

The Search for Associations of Polymorphic Variants of the COMT and MAOA Genes with Suicide Attempts in Patients with Schizophrenia: A Pilot Study

V. V. Tiguntsev, I. A. Mednova, A. N. Kornetov, D. Z. Paderina, E. G. Kornetova, and S. A. Ivanova p. 393  abstract

Cloning of Mycoplasma gallisepticum Genome in Saccharomyces cerevisiae Cells

D. R. Kharrasov, G. Yu. Fisunov, D. S. Matyushkina, E. A. Tsoy, E. A. Semenova, R. R. Kutukov, I. S. Rog, D. A. Sandanova, M. M. Borodina, and V. M. Govorun p. 404  abstract

GENOMICS. TRANSCRIPTOMICS

Optimization of Plant Recombinant Lectin Production Using a Transient Expression System in Nicotiana benthamiana

N. V. Petrova, N. G. Syrchina, A. A. Mikhailova, P. V. Mikshina, and N. E. Mokshina p. 412  abstract

CELL MOLECULAR BIOLOGY

Selective and Non-Selective Pharmacological Activation of Hypoxia-Inducible Factor Differentially Modulate Cancer Progression of Hepatocellular Carcinoma Cell Line HepG2

J. X. N. Wong, K. H. Leong, M. C. Chan, and K. W. Kong p. 423  abstract

Crol Promotes EcR Recruitment to Enhancers of Ecdysone-Dependent Genes in Drosophila melanogaster Salivary Glands

A. V. Anisimova, A. A. Evdokimova, M. M. Erokhin, D. A. Chetverina, and N. E. Vorobyeva p. 433  abstract

Cystine in Formulation Promotes the Migration and Invasion of Colon Cancer Cells with Microsatellite Instability via mTORC1 Signaling

C. Z. Yan, B. Liu, and Y. Y. Liang p. 442  abstract

M6A-Modification of SLC31A1 mRNA Promotes Cuproptosis in Unexplained Recurrent Spontaneous Abortion

J. Zhang, Y. Deng, and Y. Gao p. 452  abstract

STRUCTURAL-FUNCTIONAL ANALYSIS OF BIOPOLYMERS AND THEIR COMPLEXES

Thiophene-Hybridized Thiazole Scaffolds: Synthesis, Spectroscopic Characterization, DFT-Based NLO, NBO Property Exploration, Anticancer Screening and Molecular Docking Studies

T. H. M. Nayaka and I. Pushpavathi p. 468  abstract

Effect of ESR1 Somatic Mutations on SERM/SERD Binding: Insights from Molecular Docking and Molecular Dynamics Simulations

I. V. Margatskiy, A. M. Eliseikin, V. E. Artemov, I. O. Ponkratenko, A. E. Studennikov, and A. N. Glushkov p. 484  abstract