Vol. 59, No. 2, 2025

Molecular Biology

REVIEWS

Prognostic Potential of hsa-miR-16-5p, hsa-miR-125b-5p, and hsa-miR-181a-5p for the Formation of Groups of Increased Risk of Breast Cancer under Radiation Exposure

M. A. Yanishevskaya, E. A. Blinova, and A. V. Akleyev p. 153 abstract

Transcription Factor PAX4: Role in Differentiation of Insulin-Producing β Cells during Pancreas Development and Association with Diabetes

A. I. Melnikova, T. S. Krasnova, and P. M. Rubtsov p. 165 abstract

GENOMICS AND TRANSCRIPTOMICS

Identification of Genetic Markers of Predisposition to Thrombogenic Diseases by Minisequencing Analysis: Reagent Set “SNP2-TMG”

A. V. Grudo, I. V. Haidukevich, and G. V. Sergeev p. 175 abstract

Placental Tissue Transcriptomics as a Tool to Identify the Molecular Mechanisms of Great Obstetrical Syndromes

E. A. Trifonova, A. V. Markov, A. A. Zarubin, A. A. Babovskaya, M. M. Gavrilenko, T. V. Gabidulina, and V. A. Stepanov p. 185 abstract

CELL MOLECULAR BIOLOGY

Improving the Efficiency and Safety of Human CCR5 Gene Editing by Selection of Optimal Guide RNAs for SpCAS9 and CAS12A

R. R. Mintaev, D. V. Glazkova, J. A. Taran, E. V. Bogoslovskaya, and G. A. Shipulin p. 205 abstract

Dynamics of Transgene Expression in the MVA Vaccine Vector under the Control of the p11, p13.5, pLEO160, p7.5, and mH5 Promoters and Independence of the Transgene Expression Level from the Insertion Locus

O. V. Orlova, D. V. Glazkova, O. N. Sidorova, F. A. Urusov, G. A. Shipulin, and E. V. Bogoslovskaya p. 214 abstract

Influence of Homology Arm Length and Structure on the Efficiency of Long Transgene Integration into a Cleavage Site Induced by SpCas9 or AsCpf1

J. A. Taran, R. R. Mintaev, D. V. Glazkova, B. V. Belugin, E. V. Bogoslovskaya, and G. A. Shipulin p. 224 abstract

MLE (DHX9) Helicase Regulates the Expression of Constitutive and Inducible Isoforms of the Conserved Nuclear Receptor FTZ-F1 (NR5A3)

J. V. Nikolenko, and S. G. Georgieva p. 234 abstract

STRUCTURAL-FUNCTIONAL ANALYSIS OF BIOPOLYMERS AND THEIR COMPLEXES

πDMD Simulation as a Strategy for Refinement of AlphaFold2 Modeled Fuzzy Protein Complexes Structures

N. G. Muradyan, A. A. Sargsyan, V. G. Arakelov, A. K. Paronyan, G. G. Arakelov, and K. B. Nazaryan p. 244 abstract

Optimization of Cytotoxic Properties of Magnetic Nanoparticle-Based Doxorubicin Delivery System

A. I. Kurtova, A. V. Svetlakova, O. A. Kolesnikova, and V. O. Shipunova p. 253 abstract

BIOINFORMATICS

Division of the Standard Set of Amino Acids into Groups According to Their Evolutionary Age

V. M. Efimov, K. V. Efimov, and V. Yu. Kovaleva p. 263 abstract

METHODS

Sample Preparation and Sequencing Efficiency of microRNA Libraries from Pituitary Adenoma Tissue and Blood Plasma of Patients with Acromegaly for the Illumina Platform

E. V. Ignatieva, E. S. Nerubenko, O. A. Ivanova, U. A. Tsoy, and R. I. Dmitrieva p. 272 abstract

Efficient Method to Isolate High-Quality RNA from Mycelia of Toxigenic Fungi Fusarium sp.

A. A. Stakheev, D. Yu. Ryazantsev, N. G. Gabrielyan, A. V. Poluboyarinova, M. E. Taliansky, and S. K. Zavriev p. 285 abstract