Contents

Molecular Biology

Vol. 59, No. 1, 2025

REVIEWS

DNA Vaccine Technologies: Design and Delivery

A. A. Fando, A. A. Ilyichev, V. R. Litvinova, N. B. Rudometova, L. I. Karpenko, and A. P. Rudometov p. 1  abstract

De Novo Gene Birth

E. O. Aristova, I. A. Volkhin, A. A. Denisova, P. A. Nikitin, and E. R. Petrukhin p. 17  abstract

PSGL-1: A Universal Selectin Ligand or a Signaling Molecule? (Review of the Literature)

N. V. Korotkova, R. E. Kalinin, I. A. Suchkov, N. D. Mzhavanadze, and L. V. Nikiforova p. 26  abstract

Marine Fungi: In Search of New Antibacterial Drugs

E. A. Yurchenko, E. A. Chingizova, D. L. Aminin, and A. N. Yurchenko p. 35  abstract

Autophagy Impairment in Parkinson’s Disease: Approaches to Therapy

T. S. Usenko p. 51  abstract

GENOMICS. TRANSCRIPTOMICS

Omics Study of Ovarian Malignancies: From Urine Metabolomic Profile to Minimally Invasive MicroRNA Markers

D. S. Kutilin, O. N. Guskova, F. E. Filippov, and A. Yu. Maksimov p. 69  abstract

GENOMICS, TRANSCRIPTOMICS

NOS1AP Gene Polymorphism and Body Fat in Patients with Schizophrenia: A Search for Associations

V. V. Tiguntsev, I. A. Mednova, D. A. Petkun, A. A. Agarkov, A. N. Kornetov, I. V. Pozhidaev, D. Z. Paderina, E. G. Kornetova, and S. A. Ivanova p. 101  abstract

STRUCTURAL AND FUNCTIONAL ANALYSIS OF BIOPOLYMERS AND THEIR COMPLEXES

Substrate Efficiency of Cy5-Modified Derivatives of Deoxyuridine and Deoxycytidine in the Rolling Circle Amplification

P. A. Chirkova, S. A. Surzhikov, V. E. Kuznetsova, V. E. Shershov, A. V. Chudinov, and S. A. Lapa p. 109  abstract

Substrate Behavior of Dissimilar Cy5-Deoxypyrimidine Nucleotides in PCR with DNA Templates of Different GC Compositions

P. M. Monakova, V. E. Shershov, V. E. Kuznetsova, A. V. Chudinov, and S. A. Lapa p. 116  abstract

STRUCTURAL AND FUNCTIONAL ANALYSIS OF BIOPOLYMERS AND THEIR COMPLEXES

Mechanism of Thiocyanate Dehydrogenase Functioning Based on Structural Data

K. M. Polyakov, and S. Gavryushov p. 123  abstract

BIOINFORMATICS

Transcriptomics and the “Curse of Dimensionality”: Monte Carlo Simulations of ML-Models as a Tool for Analyzing Multidimensional Data in Tasks of Searching Markers of Biological Processes

G. J. Osmak, and M. V. Pisklova p. 135  abstract

METHODS

Development of Multiplex Real-Time RT–PCR to Determine the Expression Levels of Toll-Like Receptor Genes

S. A. Salamaikina, V. I. Korchagin, and K. O. Mironov p. 142  abstract

Erratum

Erratum to: Promoter Mutation of the bZIP Transcription Factor BdABF Accelerates Flowering in Brachypodium distachyon

B. J. Han, Z. J. Liu, W. M. Bai, F. T. Sun, Y. F. Niu, T. Y. Song, W. J. You, P. Y. Wang, N. Li, and P. S. Su p. 152  abstract