Contents

Doklady Biochemistry and Biophysics

Vol. 520, No. 1, 2025

BIOCHEMISTRY, BIOPHYSICS, AND MOLECULAR BIOLOGY

Evolutionarily Conserved DHX9/MLE Helicase Is Involved in the Regulation of Its Own mRNA Expression Level in Drosophila melanogaster

I. A. Zolin, Academician of the RAS S. G. Georgieva, and J. V. Nikolenko p. 1  abstract

Parametric Search for Optimal Channel Shape for Swirling Blood Flow in the Heart and Main Vessels

Ya. E. Zharkov, A. V. Agafonov, Alex. Y. Gorodkov, and L. A. Bockeria p. 6  abstract

Cardiac Lymph Flow Features and New Opportunities for Their Experimental Visualization

P. P. Iablonskii, A. S. Lazareva, I. A. Garapach, A. A. Iablonskaia, and Corresponding Member of the RAS S. V. Orlov p. 20  abstract

Omega-3 Docosahexaenoic Acid as a Promising Inducer of Ferroptosis: Dynamics of Action in Prostate and Colorectal Cancer Models

D. M. Olkhovik, M. O. Silkina, A. V. Razumovskaya, K. V. Klycheva, A. A. Fatkulin, T. A. Kulagin, and S. V. Nikulin p. 25  abstract

Transcriptomic Shifts in Multipotent Mesenchymal Stromal Cells during Microgravity Simulation

D. A. Yakubets, and Corresponding Member of the RAS L. B. Buravkova p. 29  abstract

Analgesic Activity of the Low Molecular Weight Neurotrophin-3 Dipeptide Mimetic GTS-301

L. G. Kolik, M. A. Konstantinopolsky, N. M. Sazonova, Corresponding Member of the RAS A. D. Durnev, and Corresponding Member of the RAS T. A. Gudasheva p. 34  abstract

New N6-Substituted Adenine Derivatives with High Antiviral Activity against RNA-Containing Viruses

A. A. Zenchenko, Yu. D. Semenova, E. R. Naberezhnaya, Ya. D. Gumennaya, A. V. Lipatova, and V. E. Oslovsky p. 38  abstract

Alteration of the Catalytic Properties of the Epoxyalcohol Synthase CYP443D1 (NvEAS) of the Starlet Sea Anemone Nematostella vectensis as a Result of a Single Amino Acid Substitution

S. S. Gorina, N. V. Lantsova, Y. Y. Toporkova, and academician A. N. Grechkin p. 42  abstract

Ascorbate Biosynthesis and Recycling Genes Are Involved in the Responses of Garlic Allium sativum L. Plants to Fusarium proliferatum Infection

A. V. Shchennikova, E. Z. Kochieva, and M. A. Filyushin p. 49  abstract

Low-molecular-weight Ligand of the Thyroid-stimulating Hormone Receptor with the Activity of a Partial Agonist and a Negative Allosteric Modulator

K. V. Derkach, E. A. Didenko, V. N. Sorokoumov, I. O. Zakharova, and A. O. Shpakov p. 53  abstract

The Influence of Triterpenoids in the Composition of Fat-Containing Products on the State of the Liver of Laboratory Animals with Acute Toxic Hepatitis

E. V. Averyanova, M. N. Shkolnikova, O. V. Chugunova, and O. N. Mazko p. 58  abstract

Assessment of Long-Term Cultivated In Vitro Willow Clones according to Chromosomal Analysis

O. S. Mashkina, and T. M. Tabatskaya p. 67  abstract

Study of the Pharmacological Activity Spectrum of the New Original NT-3 Mimetic Dipeptide GTS-302

D. M. Nikiforov, P. Yu. Povarnina, Corresponding member of the RAS T. A. Gudasheva, A. V. Nadorova, L. G. Kolik, E. A. Valdman, Yu. V. Vakhitova, and Academician S. B. Seredenin p. 74  abstract

Influence of Retrodipeptide Analogue of Cholecystokinin Tetrapeptide (GB-115) and Phenazepam on the Behavior of Rhesus Monkeys under Isolation Conditions

Al. V. Panchenko, An. V. Panchenko, L. E. Pavlova, M. F. Timina, E. V. Cherkashina, L. G. Kolik, and Academician of the RAS S. B. Seredenin p. 83  abstract

Method for Testing Drugs Belonging to Substrates and Inhibitors of the Transporter Protein BCRP on CACO-2 Cells

Yu. S. Tranova, A. A. Slepnev, I. V. Chernykh, A. V. Shchulkin, P. Yu. Mylnikov, N. M. Popova, M. I. Povetko, and E. N. Yakusheva p. 89  abstract

Mechanisms of Antitumor Activity of Low Doses of Radiation Associated with Activation of Cells’ Defense System

D. V. Fomina, L. M. Rozhdestvensky, N. F. Raeva, E. S. Vorobeva, and G. D. Zasukhina p. 96  abstract

Inhibition of Renal Cell Carcinoma Growth by 1,3-thiazin-6-one Through Targeting the Inflammatory Reaction

Hongmei Zhou, Xin Li, and Dongju Liu p. 101  abstract

Antiosteoporosis and Bone Protective Effect of Phyllanthin Against Glucocorticoid-induced Osteoporosis in Rats via Alteration of HO-1/Nrf2 and RANK/RANKL/OPG Pathway

Shaosong Sun, Yilei Liu, Xiaofeng Liu, and Panxiang Li p. 109  abstract

The Role of TRPM2 Channel in Doxorubicin-induced Cell Damage in Laryngeal Squamous Cancer Cells

Tarık Yağcı, Ramazan Çınar, Halil İbrahim Altıner, Rıza Dündar, and Kenan Yıldızhan p. 123  abstract

Chemoprotective Effect of Myrrhone against Diethylnitrosamine and Ferric Nitrile Induced Renal Cancer via Alteration of HO-1/Nrf2 and TRL4/NF-κB Signaling Pathway

Qian Yu, Ling Tian, and Jiwei Zhang p. 130  abstract

An Investigation of the Conservatism of Sequences Defining trans-Splicing in the mod(mdg4) Locus across Drosophila and Silkworm Species

O. Beginyazova, I. V. Soldatova, Academician of the RAS P. G. Georgiev, and M. V. Tikhonov p. 144  abstract

GALA3-Containing Modular Nanotransporters Are Capable of Delivering Keap1 Monobody to Target Cells and Inhibiting the Formation of Reactive Oxygen Species in the Cells

Y. V. Khramtsov, E. S. Bunin, A. V. Ulasov, T. N. Lupanova, G. P. Georgiev, and A. S. Sobolev p. 148  abstract

Functional Role of Bap170 Domains in Enhancer-Dependent Gene Activity in Drosophila melanogaster

V. K. Chmykhalo, D. Amendola, Y. V. Shidlovskii, L. A. Lebedeva, Foreign Member of the RAS P. Schedl, and E. Giordano p. 152  abstract