Contents

Doklady Biochemistry and Biophysics

Vol. 496, No. 1, 2021

Biochemistry, Biophysics, and Molecular Biology

MLE Helicase Is a New Participant in the Transcription Regulation of the ftz-f1 Gene Encoding Nuclear Receptor in Higher Eukaryotes

J. V. Nikolenko, M. M. Kurshakova, A. N. Krasnov and Corresponding Member of the RAS S. G. Georgieva p. 1  abstract

Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase

A. K. Beilin, N. G. Gurskaya, N. A. Evtushenko, E. V. Alpeeva, A. V. Kosykh, V. V. Terskikh, Corresponding Member of the RAS A. V. Vasiliev and Corresponding Member of the RAS E. A. Vorotelyak p. 5  abstract

Bis(µ-Tartrato)Di(μ-Hydroxy) Germanate (IV) Triethanolammonium as a Mononuclear Alkaline Phospholipase A2 Inhibitor

Academician P. A. Storozhenko, M. M. Rasulov, I. V. Zhigacheva and V. P. Baryshok p. 10  abstract

Rational Design and Mutagenesis of Fungal Luciferase from Neonothopanus nambi

K. A. Beregovaya, N. M. Myshkina, T. V. Chepurnykh, A. A. Kotlobay, K. V. Purtov, V. N. Petushkov, N. S. Rodionova and I. V. Yampolsky p. 14  abstract

Study of the Interaction between Xmas-2, the Main Protein of TREX-2 mRNA Export Complex, and the Orc3 Protein, a Subunit of ORC Complex of D. melanogaster

M. M. Kurshakova, D. V. Kopytova and Corresponding Member of the RAS S. G. Georgieva p. 18  abstract

Interchromosomal Contacts of rDNA Clusters in Three Human Cell Lines Are Associated with Silencing of Genes Controlling Morphogenesis

N. A. Tchurikov, E. S. Klushevskaya, Y. V. Kravatsky, G. I. Kravatskaya and D. M. Fedoseeva p. 22  abstract

Novel Negative Sense Genes in the RNA Genome of Coronaviruses

Corresponding Member of the RAS O. P. Zhirnov and S. V. Poyarkov p. 27  abstract

GSK3 Kinase Inhibitor, CHIR, Suppress Transcription of Tissue Specific POU2F1 Isoform in Burkitt Namalwa Lymphoma Cells

E. V. Pankratova, T. N. Portseva, A. A. Makarova, Academician Yu. V. Ilyin, A. G. Stepchenko and Corresponding Member of the RAS S. G. Georgieva p. 32  abstract

Effectiveness of the Sequential Use of Plastic and Titanium Implants for Experimental Replacement of the Mandibular Defect in Animals Using Preliminary Digital Design

Al. Al. Dolgalev, D. S. Svyatoslavov, V. A. Pout, Academician I. V. Reshetov and I. V. Kastyro p. 36  abstract

Differences in Fatty Acid Composition between Orb-Weaver Spiders Inhabiting a Riparian Zone and a Steppe Are Associated with the Consumption of Different Chironomid Taxa

N. N. Sushchik, E. V. Borisova, I. A. Demina (Vitkovskaya), O. N. Makhutova and Corresponding Member of the RAS M. I. Gladyshev p. 40  abstract

Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection

Corresponding Member of the RAS S. D. Varfolomeev, S. V. Zhuravel, A. A. Panin, L. V. Shogenova, V. I. Bykov, S. B. Tsybenova, A. M. Ryabokon, I. I. Utkina, P. V. Gavrilov and A. G. Chuchalin p. 44  abstract

Production of a Cloned Offspring and CRISPR/Cas9 Genome Editing of Embryonic Fibroblasts in Cattle

G. N. Singina, P. V. Sergiev, A. V. Lopukhov, M. P. Rubtsova, N. P. Taradajnic, N. V. Ravin, E. N. Shedova, T. E. Taradajnic, I. A. Polejaeva, A. V. Dozev, Foreign Member of the RAS G. Brem, Academician O. A. Dontsova and Academician N. A. Zinovieva p. 48  abstract

The Recombinant Luciferase of the Fungus Neonothopanus nambi: Obtaining and Properties

A. Yu. Gorokhovatsky, T. V. Chepurnykh, A. S. Shcheglov, Yu. A. Mokrushina, M. N. Baranova, S. A. Goncharuk, K. V. Purtov, V. N. Petushkov, N. S. Rodionova and I. V. Yampolsky p. 52  abstract

Preventive Effect of Saussurea lappa Extract on Osteoarthritis in Mice Model through Inhibition of NF-κB Pathway

Dong Feng and Xiaohu Zhu p. 56  abstract