Contents

Biochemistry (Moscow)

Vol. 91, No. 7, 2026

REVIEW

Chemically Induced Dimerization Systems: From FKBP/FRB Engineering to Expanded Biological Applications

Hui Yuan, Shuo Lin, Ziyi Lin, Shuangpeng Li, Xia Zuo, Haihua Yin, Ruilin Cheng, Yuqian Tang, Zihao Luo, Min Chen, and Qingjian Zou p. 1051  abstract

Extrachromosomal DNA in Oncology: History of Discovery, Research Methods, and Current Perspectives

Vera S. Mukhina and Alexander V. Favorov p. 1073  abstract

Glycosylase Base Editors: New Tools for Genome Editing

Liliya M. Kulishova and Dmitry O. Zharkov p. 1093  abstract

Aptamer Sensors for Inflammaging Biomarkers: Principles of Molecular Recognition, Analytical Platforms, and Unaddressed Targets

Nataliya O. Kudryashova, Igor V. Dobrokhotov, Elizaveta S. Ershova, and Alexey A. Moskalev p. 1114  abstract

Dysfunction of Primary Cilium in Huntington’s Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub

Aleksandra S. Churkina, Anton S. Shakhov, and Irina B. Alieva p. 1137  abstract

Differential S-Acylation of Viral and Cellular Proteins: Structural Determinants, Enzymes, and Putative Functional Implications

Larisa V. Kordyukova, Marina V. Serebryakova, Irina S. Panina, and Michael Veit p. 1157  abstract

Substrate Specificity of T4 RNA Ligase 1 in Intramolecular Ligation of Single-Stranded DNA

Assol R. Sakhabutdinova, Ayzilya A. Shakirova, and Ravil R. Garafutdinov p. 1174  abstract

The Levels of Neurotrophic Factors in the Rat Hippocampus in the Acute Period after Middle Cerebral Artery Occlusion Are Associated with the Hypothalamic–Pituitary–Adrenal Axis Activation

Mikhail V. Onufriev, Yulia V. Moiseeva, Margarita R. Novikova, Pavel A. Kostryukov, and Natalia V. Gulyaeva p. 1187  abstract

Effects of the C.886C>T Mutation in the Mouse Tyrosine Hydroxylase Gene on Behavior and Dopamine System of the Brain

Ismail Alsalloum, Ilya A. Rakhov, Polina D. Komleva, Valentina N. Kuranova, Anastasia E. Bastrikova, Alexander V. Kulikov, and Darya V. Bazovkina p. 1200  abstract

Remodeling of Colorectal Cancer Extracellular Matrix after Radiotherapy

Sahil V. Amikishiev, Darya O. Kuzmina, and Arseniy E. Yuzhalin p. 1216  abstract

Secreted Cyclophilin A Induces M1 and M2 Macrophage Polarization in the THP-1 Model in vitro

Anastasiia A. Kalinina, Marina V. Kubekina, Maria A. Zamkova, Nadezhda A. Persiyantseva, Alexandra V. Bruter, Dmitry B. Kazansky, and Ludmila M. Khromykh p. 1230  abstract

Regulation of Neutrophil Adhesion and Immune Response: Influence of ATP, Adenosine, and Iodoacetic Acid

Svetlana I. Galkina, Ekaterina A. Golenkina, Alexander L. Ksenofontov, Marina V. Serebryakova, Larisa V. Kordyukova, Natalia V. Fedorova, Vladimir I. Stadnichuk, Ludmila A. Baratova, and Galina F. Sud’ina p. 1241  abstract

Generation of Bacteriochlorophyll Triplets by the Mutant Reaction Center of Cereibacter sphaeroides G(M71)L/A(M260)W

Tatiana Yu. Fufina, Ivan I. Proskuryakov, Irina B. Klenina, and Lyudmila G. Vasilyeva p. 1256  abstract

Thermal Inactivation of Penicillin Acylase from Escherichia coli: Rate-Limiting Step and Role of Protein Aggregation

Tatiana A. Shcherbakova, Nikolai V. Panin, and Vytas K. Švedas p. 1265  abstract

Monitoring Early Efficacy of the Checkpoint Immunotherapy Based on Fluorescence Lifetime Imaging Microscopy of the Patient-Derived Lymphocyte Subsets

Diana V. Yuzhakova, Anastasia I. Kononova, Anna V. Izosimova, Margarita M. Sazhina, Ilya D. Shchechkin, Artem M. Mozherov, Pavel A. Bureev, Dmitry A. Kuzmin, Alena I. Gavrina, Irina S. Shumskaya, Sergey V. Gamayunov, and Marina V. Shirmanova p. 1276  abstract