Contents

Biochemistry (Moscow)

Vol. 89, No. 7, 2024

Pharmacological Doses of Thiamine Benefit Patients with the Charcot–Marie–Tooth Neuropathy by Changing Thiamine Diphosphate Levels and Affecting Regulation of Thiamine-Dependent Enzymes

Artem V. Artiukhov, Olga N. Solovjeva, Natalia V. Balashova, Olga P. Sidorova, Anastasia V. Graf, and Victoria I. Bunik p. 1161  abstract

Use of qPCR to Evaluate Efficiency of the Bulky DNA Damage Removal in Extracts of Mammalian Cells with Different Maximum Lifespan

Aleksei A. Popov, Vladimir A. Shamanin, Irina O. Petruseva, Aleksei N. Evdokimov, and Olga I. Lavrik p. 1183  abstract

REVIEW

Genetic Features of Lipid and Carbohydrate Metabolism in Arctic Peoples

Boris A. Malyarchuk p. 1192  abstract

Mechanism of PARP1 Elongation Reaction Revealed by Molecular Modeling

Sergey V. Pushkarev, Evgeny M. Kirilin, Vytas K. Švedas, and Dmitry K. Nilov p. 1202  abstract

Extracellular Vesicle miRNAs in Diagnostics of Gastric Cancer

Gleb O. Skryabin, Anastasiya A. Beliaeva, Adel D. Enikeev, and Elena M. Tchevkina p. 1211  abstract

Dermal Fibroblast Cell Line from a Patient with the Huntington’s Disease as a Promising Model for Studying Disease Pathogenesis: Production and Characterization

Nina Kraskovskaya, Anna Koltsova, Polina Parfenova, Alla Shatrova, Natalya Yartseva, Vladimir Nazarov, Ekaterina Devyatkina, Mikhail Khotin, and Natalia Mikhailova p. 1239  abstract

Content of Primary and Secondary Carotenoids in the Cells of Cryotolerant Microalgae Chloromonas reticulata

Olga V. Dymova, Vitaliy S. Parshukov, Irina V. Novakovskaya, and Elena N. Patova p. 1251  abstract

Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain

Nikolai N. Sluchanko, Dmitry V. Shcheblyakov, Larisa A. Varfolomeeva, Irina A. Favorskaya, Inna V. Dolzhikova, Anastasia I. Korobkova, Irina A. Alekseeva, Ilias B. Esmagambetov, Artem A. Derkaev, Vladimir V. Prokofiev, Ilya D. Zorkov, Denis Y. Logunov, Alexander L. Gintsburg, Vladimir O. Popov, and Konstantin M. Boyko p. 1260  abstract

Cardiac Myosin and Thin Filament as Targets for Lead and Cadmium Divalent Cations

Oksana P. Gerzen, Iulia K. Potoskueva, Alena E. Tzybina, Tatiana A. Myachina, and Larisa V. Nikitina p. 1273  abstract

Multi-Directional Mechanisms of Participation of the TRIM Gene Family in Response of Innate Immune System to Bacterial Infections

Valentina V. Nenasheva, Ekaterina A. Stepanenko, and Vyacheslav Z. Tarantul p. 1283  abstract

Dose-Dependent Alterations of Lysosomal Activity and Alpha-Synuclein in Peripheral Blood Monocyte-Derived Macrophages and SH-SY5Y Neuroblastoma Cell Line by upon Inhibition of MTOR Protein Kinase – Assessment of the Prospects of Parkinson’s Disease Therapy

Anastasia I. Bezrukova, Katerina S. Basharova, Galina V. Baydakova, Ekaterina Y. Zakharova, Sofya N. Pchelina, and Tatiana S. Usenko p. 1300  abstract

Femtosecond Dynamics of the Excited Primary Electron Donor in Reaction Centers of the Purple Bacterium Rhodobacter sphaeroides

Anton M. Khristin, Tatyana Yu. Fufina, and Ravil A. Khatypov p. 1313  abstract

Mechanism of Stimulation of Myogenesis under the Action of Succinic Acid through the Succinate Receptor SUCNR1

Yuliya V. Abalenikhina, Mariya O. Isayeva, Pavel Yu. Mylnikov, Alexey V. Shchulkin, and Elena N. Yakusheva p. 1325  abstract

Differences in the Effect of Beta-Hydroxybutyrate on the Mitochondrial Biogenesis, Oxidative Stress and Inflammation Markers in Tissues from Young and Old Rats

Veronika V. Nesterova, Polina I. Babenkova, Anna A. Brezgunova, Natalia A. Samoylova, Irina S. Sadovnikova, Dmitry S. Semenovich, Nadezda V. Andrianova, Artem P. Gureev, and Egor Y. Plotnikov p. 1336  abstract