Contents
Biochemistry (Moscow)
Vol. 90, No. 6, 2025
Preface to the Special Issue “Genetic Technologies in Medicine, Agriculture, and Biotechnology”
Dmitry S. Kostyushev, and Andrey A. Zamyatnin Jr. p. 649 abstract
The Role of m6A-RNA Methylation in the Development, Progression, and Treatment Response of Bladder Cancer
Tatiana Sinyagovskaya, Yuliya Li, Natalya Vinchevskaya-Khmelnitskaya, Aisha Agabalaeva, Natalia Ponomareva, Sergey Brezgin, Irina Goptar, Vladimir Chulanov, Alim Dymov, Andrey Vinarov, Dmitry Kostyushev, and Anastasiya Kostyusheva p. 650 abstract
Diagnostic and Prognostic Potential of Circulating miR-1301-3p, miR-106a-5p, miR-129-5p, miR-3613-3p, and miR-647 microRNAs in Gastric Cancer
Irina V. Bure, Ekaterina A. Vetchinkina, Alexei I. Kalinkin, Ekaterina B. Kuznetsova, Alevtina E. Kiseleva, Ekaterina A. Alekseeva, Nikolay S. Esetov, and Marina V. Nemtsova p. 671 abstract
Transcriptional Biomarkers in the Diagnosis of Genetic Disorders: Opportunities, Challenges, and Prospects for Application
Lidia N. Nefedova, and Tatiana N. Krasnova p. 683 abstract
Telomere Length and Telomerase Activity as Biomarkers in the Diagnostics and Prognostics of Pathological Conditions
Elizaveta Yu. Moskaleva, Alexander I. Glukhov, Alexander S. Zhirnik, Olga V. Vysotskaya, and Svetlana A. Vorobiova p. 700 abstract
Selection of UTRs in mRNA-Based Gene Therapy and Vaccines
Ilya A. Volkhin, Anastasia Iu. Paremskaia, Maria A. Dashian, Darya S. Smeshnova, Roman E. Pavlov, Olga N. Mityaeva, Pavel Yu. Volchkov, and Andrei A. Deviatkin p. 725 abstract
Multiepitope mRNA Vaccine mRNA-mEp21-FL-IDT Provides Efficient Protection against M. tuberculosis
Alisa A. Kazakova, Galina S. Shepelkova, Ivan S. Kukushkin, Vladimir V. Yeremeev, Roman A. Ivanov, and Vasiliy V. Reshetnikov p. 754 abstract
Selection of Optimal pegRNAs to Enhance Efficiency of Prime Editing in AT-Rich Genome Regions
Olga V. Volodina, Anna G. Demchenko, Arina A. Anuchina, Oxana P. Ryzhkova, Valeriia A. Kovalskaya, Ekaterina V. Kondrateva, Vyacheslav Y. Tabakov, Alexander V. Lavrov, and Svetlana A. Smirnikhina p. 773 abstract
Progress in CRISPR/Cas13-Mediated Suppression of Influenza A and SARS-CoV-2 Virus Infection in in vitro and in vivo Models
Alisa A. Kazakova, Elena I. Leonova, Julia V. Sopova, Angelina V. Chirinskaite, Ekaterina S. Minskaya, Ivan S. Kukushkin, Roman A. Ivanov, and Vasiliy V. Reshetnikov p. 786 abstract
Biotechnological Approaches to Plant Antiviral Resistance: CRISPR-Cas or RNA Interference?
Natalia O. Kalinina, Nadezhda A. Spechenkova, and Michael E. Taliansky p. 804 abstract
Designing a Thermostable Mini-Intein for Intein-Mediated Purification of Recombinant Proteins and Peptides
Andrey A. Karanov, Evgeniy A. Zayats, Maria A. Kostromina, Yulia A. Abramchik, Aleksandra R. Sharafutdinova, Maria S. Surkova, Andrey A. Zamyatnin Jr., and Roman S. Esipov p. 818 abstract