Contents

Biochemistry (Moscow)

Vol. 89, No. 6, 2024

REVIEW

Irreducible Complexity of Hox Gene: Path to the Canonical Function of the Hox Cluster

Milana A. Kulakova, Georgy P. Maslakov, and Liudmila O. Poliushkevich p. 987  abstract

Methods for Functional Characterization of Genetic Polymorphisms of Non-Coding Regulatory Regions of the Human Genome

Aksinya N. Uvarova, Elena A. Tkachenko, Ekaterina M. Stasevich, Elina A. Zheremyan, Kirill V. Korneev, and Dmitry V. Kuprash p. 1002  abstract

Activity of DNA Repair Systems in the Cells of Long-Lived Rodents and Bats

Aleksei A. Popov, Irina O. Petruseva, and Olga I. Lavrik p. 1014  abstract

The C886T Mutation in the Th Gene Reduces the Activity of Tyrosine Hydroxylase in the Mouse Brain

Ismail Alsalloum, Vitalii S. Moskaliuk, Ilya A. Rakhov, Daria V. Bazovkina, and Alexander V. Kulikov p. 1024  abstract

Unique Properties of Synaptosomes and Prospects for Their Use for the Treatment of Alzheimer’s Disease

Alla S. Dashkova, Vladimir I. Kovalev, Alina V. Chaplygina, Daria Yu. Zhdanova, and Natalia V. Bobkova p. 1031  abstract

Astrocytic NMDA Receptors

Artem M. Kosenkov, Sergei A. Maiorov, and Sergei G. Gaidin p. 1045  abstract

Pore-Forming VDAC Proteins of the Outer Mitochondrial Membrane: Regulation and Pathophysiological Role

Natalia V. Belosludtseva, Mikhail V. Dubinin, and Konstantin N. Belosludtsev p. 1061  abstract

Formation of Amyloid-Like Conformational States of β-Structured Membrane Proteins on the Example of OMPF Porin from the Yersinia pseudotuberculosis Outer Membrane

Olga D. Novikova, Tatyana V. Rybinskaya, Elena A. Zelepuga, Vladimir N. Uversky, Nataliya Yu. Kim, Ekaterina A. Chingizova, Ekaterina S. Menchinskaya, Valentina A. Khomenko, Dmitriy K. Chistyulin, and Olga Yu. Portnyagina p. 1079  abstract

Design, in silico Evaluation, and Determination of Antitumor Activity of Potential Inhibitors Against Protein Kinases: Application to BCR-ABL Tyrosine Kinase

Elena V. Koroleva, Anastasiya L. Ermolinskaya, Zhanna V. Ignatovich, Yury V. Kornoushenko, Alesia V. Panibrat, Vladimir I. Potkin, and Alexander M. Andrianov p. 1094  abstract

Key Enzymes of the Serotonergic System – Tryptophan Hydroxylase 2 and Monoamine Oxidase A – In the Brain of Rats Selectively Bred for a Reaction toward Humans: Effects of Benzopentathiepin TC-2153

Vitalii S. Moskaliuk, Rimma V. Kozhemyakina, Tatyana M. Khomenko, Konstantin P. Volcho, Nariman F. Salakhutdinov, Alexander V. Kulikov, Vladimir S. Naumenko, and Elizabeth A. Kulikova p. 1109  abstract

Post-Integrational DNA Repair of HIV-1 Is Associated with Activation of the DNA-PK and ATM Cellular Protein Kinases and Phosphorylation of Their Targets

Andrey N. Anisenko, Anastasiia A. Nefedova, Igor I. Kireev, and Marina B. Gottikh p. 1122  abstract

Specificity of Photochemical Energy Conversion in Photosystem I from the Green Microalga Chlorella ohadii

Dmitry A. Cherepanov, Anastasiya A. Petrova, Mariya S. Fadeeva, Fedor E. Gostev, Ivan V. Shelaev, Victor A. Nadtochenko, and Alexey Yu. Semenov p. 1133  abstract

The Antioxidant Defense System of Tomato (Solanum lycopersicum L.) Varieties under Drought Stress and upon Post-Drought Rewatering

Naima N. Niyazova, and Irada M. Huseynova p. 1146  abstract

Erratum

Erratum to: Rational Design of Drugs Targeting G-Protein-Coupled Receptors: A Structural Biology Perspective

Polina A. Khorn, Aleksandra P. Luginina, Vladimir A. Pospelov, Dmitrii E. Dashevsky, Andrey N. Khnykin, Olga V. Moiseeva, Nadezhda A. Safronova, Anatolii S. Belousov, Alexey V. Mishin, and Valentin I. Borshchevsky p. 1158  abstract

Erratum to: Rational Design of Drugs Targeting G-Protein-Coupled Receptors: Ligand Search and Screening

Aleksandra P. Luginina, Andrey. N. Khnykin, Polina A. Khorn, Olga V. Moiseeva, Nadezhda A. Safronova, Vladimir A. Pospelov, Dmitrii E. Dashevskii, Anatolii S. Belousov, Valentin I. Borschevskiy, and Alexey V. Mishin p. 1159  abstract