Contents

Biochemistry (Moscow)

Vol. 91, No. 5, 2026

REVIEW

Metabolic Neurophilosophy: Linking Brain Function with Body Metabolism

Natalia V. Gulyaeva p. 623  abstract

Integrating Dopamine and BDNF Hypotheses: The Role of Dopamine–BDNF Crosstalk in Neuropathologies

Marah Alsalloum, Anton Tsybko, and Vladimir Naumenko p. 637  abstract

Sphingosine-1-Phosphate Is a Key Signaling Molecule in Normal Conditions and in Multiple Sclerosis

Dmitry A. Ganin and Mariya N. Zakharova p. 658  abstract

The Roles of Corticosterone, Interleukin-1β, and Their Interactions in the Development of Stress-Induced Anxiety-Like Behavior in Laboratory Rodents

Anisa I. Vysotskaya and Galina T. Shishkina p. 676  abstract

Hypothalamic Regulation of the Gonadal Axis and Roles of Leptin and Insulin in It

Inna I. Zorina, Kira V. Derkach, and Alexander O. Shpakov p. 688  abstract

BDNF as a Mediator between Body Metabolism and Brain Function in Health and Disease: The Case of Alcohol Dependence

Danil I. Peregud and Nataliya V. Gulyaeva p. 713  abstract

Metabolic Reprogramming of Astrocytes and Microglia as a Driver and Therapeutic Target in Epileptogenesis

Maria V. Zakharova, Anna A. Kovalenko, Yuliy A. Gorgul, Aleksandr P. Schwarz, Olga E. Zubareva, Adelia R. Kharisova, Georgy P. Diespirov, and Aleksey V. Zaitsev p. 733  abstract

Method for Individual Assessment of Human Cerebral Cortex Activity by a Combined Use of Magnetic Resonance Spectroscopy of Glutamate and BOLD Signal Method

Aleksandr D. Korotkov, Artem D. Myznikov, Ilya M. Krasnov, Mikhail D. Didur, Denis V. Cherednichenko, and Maxim V. Kireev p. 770  abstract

Immunoinflammatory Markers in Patients with Affective Disorders: Genetic Polymorphisms, Peripheral Cytokine Levels, and Expression of IL-1β, IL-13, TNF-β, and TGF-α in Peripheral Blood Mononuclear Cells

Ekaterina V. Mikhalitskaya, Lyudmila A. Levchuk, Anastasia S. Boiko, Natalya M. Vyalova, Elena V. Epimakhova, Diana Z. Paderina, Olga V. Roschina, German G. Simutkin, Nikolay A. Bokhan, and Svetlana A. Ivanova p. 780  abstract

A Conjugate of Aminoadamantane and Tetrahydro-γ-Carboline Inhibits Accumulation of Mutant α-Synuclein A53T in the Cellular Model of Proteinopathy

Marina V. Burak, Nadezhda E. Pukaeva, Victoria S. Kryshkova, Olga A. Kukharskaya, Maya R. Nazdracheva, Sergey A. Pukhov, Kirill A. Rachenkov, Alla V. Stavrovskaya, Vladimir P. Fisenko, Michail S. Kukharsky, and Sergei O. Bachurin p. 789  abstract

Effect of the PPARγ Agonist Pioglitazone on Rat Behavior and Expression of Epileptogenesis-Related Genes during the Latent Phase of the Lithium-Pilocarpine Model

Adeliya R. Kharisova, Olga E. Zubareva, Anna A. Kovalenko, Denis S. Sinyak, and Aleksey V. Zaitsev p. 800  abstract

Dependence of Antioxidant and Transcriptional Responses to Periodic Hypoxia on Sex and Age in Rats

Sofia D. Kabiolskaya, Olga I. Patiavina, Ilia A. Kabiolskiy, Olga K. Savushkina, Elena B. Tereshkina, Tatiana A. Prokhorova, Elena A. Sebentsova, and Natalia G. Levitskaya p. 816  abstract

Multidirectional Effects of SARS-CoV-2 Coronavirus Proteins on Amyloid Transformation of Alpha-Synuclein

Yulia Y. Stroylova, Anastasiya V. Konstantinova, Denis V. Pozdyshev, Ivan A. Katrukha, Reza Yousefi, and Vladimir I. Muronetz p. 836  abstract