Contents

Biochemistry (Moscow)

Vol. 90, No. 4, 2025

REVIEW

Novel CRISPR/Cas9-Based Approaches for Quantitative Study of DSB Repair Mechanics

Alexander V. Smirnov and Anastasia M. Yunusova p. 437  abstract

Pyruvate Kinase PKM2: Basic and Translational Aspects in Molecular Diagnosis of Human Malignancies

Pavel V. Belousov p. 457  abstract

Suppression of Il5 and Il13 Gene Expression by Synthetic siRNA Molecules Reduces Nasal Hyperreactivity and Inflammation in a Murine Model of Allergic Rhinitis

Mariya M. Kaganova, Igor P. Shilovskiy, Valeriya I. Kovchina, Ekaterina D. Timotievich, Tatiana E. Rusak, Alexander A. Nikolskii, Kirill V. Yumashev, George B. Pasikhov, Kamilla V. Vinogradova, Danila A. Gurskii, Maya V. Popova, Vera E. Brylina, and Musa R. Khaitov p. 476  abstract

R- and S-Pyruvate-Containing Polysaccharide from the Cell Wall of Rathayibacter sp. VKM Ac-2927

Maksim S. Kokoulin, Natalia V. Potekhina, Elena M. Tul’skaya, Yury V. Ospennikov, and Lyudmila I. Evtushenko p. 493  abstract

Restriction–Modification Systems Specific toward GGATC, GATGC, and GATGG. Part 1. Evolution and Ecology

Sergey Spirin, Ivan Rusinov, Olga Makarikova, Andrei Alexeevski, and Anna Karyagina p. 502  abstract

Restriction–Modification Systems Specific toward GGATC, GATGC, and GATGG. Part 2. Functionality and Structure

Sergey Spirin, Alexander Grishin, Ivan Rusinov, Andrei Alexeevski, and Anna Karyagina p. 513  abstract

Comparative Analysis of Mesophyll and Bundle Sheath Chloroplasts from Maize Plants Subjected to Salt Stress

Nahida Kh. Aliyeva, Durna R. Aliyeva, Saftar Y. Suleymanov, Fuad H. Rzayev, Eldar K. Gasimov, and Irada M. Huseynova p. 522  abstract

Unveiling Oncogenic Power of WAVE1 in Bladder Cancer Progression

Shouxi Cui, Bin Liang, and Yong Liu p. 534  abstract

Depot-Specific Changes in Gene Expression in the Inguinal and Epididymal Adipose Tissues in Response to the High-Intensity Interval Training and Moderate-Intensity Continuous Training in Mice

Yisheng Luan, Lingfeng Yuan, Mingyue Wang, Bing Zhang, Yao Liu, Yingzhe Xiong, and Yaxin Wang p. 544  abstract