Contents

Biochemistry (Moscow)

Vol. 89, No. 2, 2024

EDITORIAL NOTES

Preface to the Special Issue: The Skulachev Project

Maxim V. Skulachev p. 197  abstract

Retinoprotective Effect of SkQ1, Visomitin Eye Drops, Is Associated with Suppression of P38 MAPK and ERK1/2 Signaling Pathways Activity

Natalia A. Muraleva, Anna A. Zhdankina, Anzhella Zh. Fursova, and Nataliya G. Kolosova p. 201  abstract

Relationship of Cytotoxic and Antimicrobial Effects of Triphenylphosphonium Conjugates with Various Quinone Derivatives

Pavel A. Nazarov, Lyudmila A. Zinovkina, Anna A. Brezgunova, Konstantin G. Lyamzaev, Andrei V. Golovin, Marina V. Karakozova, Elena A. Kotova, Egor Yu. Plotnikov, Roman A. Zinovkin, Maxim V. Skulachev, and Yuri N. Antonenko p. 212  abstract

REVIEW

Mitocentricity

Dmitry B. Zorov, Polina A. Abramicheva, Nadezda V. Andrianova, Valentina A. Babenko, Ljubava D. Zorova, Savva D. Zorov, Irina B. Pevzner, Vasily A. Popkov, Dmitry S. Semenovich, Elmira I. Yakupova, Denis N. Silachev, Egor Y. Plotnikov, and Gennady T. Sukhikh p. 223  abstract

A Redox-Regulated, Heterodimeric NADH:cinnamate Reductase in Vibrio ruber

Yulia V. Bertsova, Marina V. Serebryakova, Victor A. Anashkin, Alexander A. Baykov, and Alexander V. Bogachev p. 241  abstract

Safari with an Electron Gun: Visualization of Protein and Membrane Interactions in Mitochondria in Natural Environment

Semen V. Nesterov, Konstantin S. Plokhikh, Yuriy M. Chesnokov, Denis A. Mustafin, Tatyana N. Goleva, Anton G. Rogov, Raif G. Vasilov, and Lev S. Yaguzhinsky p. 257  abstract

Organ Frame Elements or Free Intercellular Gel-Like Matrix as Necessary Conditions for Building Organ Structures during Regeneration

Vasily N. Manskikh p. 269  abstract

Enhanced ROS Production in Mitochondria from Prematurely Aging mtDNA Mutator Mice

Irina G. Shabalina, Daniel Edgar, Natalia Gibanova, Anastasia V. Kalinovich, Natasa Petrovic, Mikhail Yu. Vyssokikh, Barbara Cannon, and Jan Nedergaard p. 279  abstract

Age-Dependent Changes in the Production of Mitochondrial Reactive Oxygen Species in Human Skeletal Muscle

Mikhail Yu. Vyssokikh, Maksim A. Vigovskiy, Vladislav V. Philippov, Yakov R. Boroday, Mariya V. Marey, Olga A. Grigorieva, Tatiana F. Vepkhvadze, Nadezhda S. Kurochkina, Ludmila A. Manukhova, Anastasiya Yu. Efimenko, Daniil V. Popov, and Vladimir P. Skulachev p. 299  abstract

AgeMeta: Quantitative Gene Expression Database of Mammalian Aging

Stanislav Tikhonov, Mikhail Batin, Vadim N. Gladyshev, Sergey E. Dmitriev, and Alexander Tyshkovskiy p. 313  abstract

Evolution of Longevity in Tetrapods: Safety Is More Important than Metabolism Level

Gregory A. Shilovsky, Tatyana S. Putyatina, and Alexander V. Markov p. 322  abstract

Exploring Patterns of Human Mortality and Aging: A Reliability Theory Viewpoint

Leonid A. Gavrilov, and Natalia S. Gavrilova p. 341  abstract

Biological Clocks: Why We Need Them, Why We Cannot Trust Them, How They Might Be Improved

Josh Mitteldorf p. 356  abstract

MINI-REVIEW

Two Types of Survival Curves of Different Lines of Progeric Mice

Svyatoslav S. Sokolov, and Fedor F. Severin p. 367  abstract

DISCUSSION

Calculating Aging: Analysis of Survival Curves in the Norm and Pathology, Fluctuations in Mortality Dynamics, Characteristics of Lifespan Distribution, and Indicators of Lifespan Variation

Gregory A. Shilovsky p. 371  abstract

REVIEW

Developing Peripheral Biochemical Biomarkers of Brain Disorders: Insights from Zebrafish Models

Nikita P. Ilyin, Elena V. Petersen, Tatyana O. Kolesnikova, Konstantin A. Demin, Sergey L. Khatsko, Kirill V. Apuhtin, and Allan V. Kalueff p. 377  abstract