Contents

Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry

Vol. 20, No. 2, 2026

Proteases in Medicine: Unlocking Therapeutic and Clinical Potential of Nature’s Catalysts

Trivedi Mansi and Patadia Hemantkumar p. 117  abstract

Diagnostic Accuracy and Clinical Significance of IGF-1 and C-Peptide as Biomarkers for Insulin Resistance in Weight-Stable Obese Patients: A Comparative ROC Curve Analysis

Heba Saad Assal, Sara Abdullah Kamil, and Fatima Abdulkareem Eraibi p. 138  abstract

Physicochemical Analysis of Extracellular Nanovesicles and Exosome-Like Nanovesicles

K. S. Evmenov, E. A. Tkachenko, S. A. Brezgin, A. P. Kostyusheva, N. I. Ponomareva, P. A. Demina, L. Fatkhutdinova, M. V. Zyuzin, and D. S. Kostyushev p. 145  abstract

Association between Serum Metallothionein 2, Metallothionein 4, and Other Biochemical Aspects in Iraqi Infertile Women

Israa T. Ali and Ali W. Al-Ani p. 159  abstract

Effects of High-Intensity Interval Training with Varying Rest Periods on Tryptophan and TMAO Levels in Young Football Players

Hüsamettin Vatansev, Mehmet Pense, Fatma Akat, Mohammad Ahmad Bik, Ömer Çalişkan, and Eissa Almaghrebi p. 168  abstract

Predictive Value of TSH for Cardiovascular Risk Markers in Subclinical Hypothyroidism: Focus on CRP, AIP, and HbA1c

Awat Hamad Awla, Fatima Mohammed Ahmed, Wafa Ahmed Hamadameen, Arazw hamad Awla, and Zanyar Khalid Hama p. 178  abstract

Characterization of Early Dose-Related Hepatic Alterations Following Acute Cisplatin Exposure in Rats

Gulsum Abusoglu, Melek Altunkaya, and Bahadır Öztürk p. 188  abstract

Interplay Between Klotho and IL-6 in Diabetic Kidney Disease: Inflammation, Mineral Dysregulation, and Renal Dysfunction

Mustafa A. Mahdi and Dhifaf Z. Aziz p. 196  abstract

Standardization and Streamlining of Escherichia coli Cultivation for Bioactive Peptide Production Using a Quality by Design Approach

E. A. Buslaeva, M. D. Bochkareva, Z. R. Khasanshina, I. A. Kornakov, D. A. Senichkina, V. I. Shmurak, A. A. Filipenko, and R. V. Drai p. 211  abstract

Influence of Origanum vulgare L. on Adenosine Deaminase Activity

A. Antonyan, R. Balagyozyan, A. Bakaryan, A. Avetisyan, V. Mukuchyan, L. Karapetyan, and S. Mardanyan p. 221  abstract