Partial Molar Volumes of Glycyrrhizic Acid in Ethanol
and Dimethylformamide

O. A. Kolyadina and Yu. I. Murinov

Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa,
450054 Bashkortostan, Russia

Received November 28, 1995

Abstract—The densities of glycyrrhizic acid (GA) solutions in ethanol and dimethylformamide (DMF) were
measured at 20–50°C in the GA concentration range 0–0.55 mol/dm³. The apparent (V_a) and partial () molar
volumes of glycyrrhizic acid in both solvents were calculated from the data obtained. It was found that the GA
partial molar volume depends linearly on the concentration, an observation which indicates the absence of spe-
cific interactions in the systems considered. The results were explained by the formation of inclusion com-
pounds. The calculated values of r, the ratio of GA empty volumes in the solution and in the pure state, confirm
the experimental data. These results characterize ethanol as a structure-creating solvent and DMF as a structure-
destroying one in the GA concentration range from 0 to 0.014 mol/dm³; DMF is inert outside this region.

Pleiades Publishing home page | journal home page | top

If you have any problems with this server, contact webmaster.