A. V. Vyushina, A. V. Pritvorova, O. G. Semenova, V. G. Shalyapina†, and M. A. Flerov1
Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia
Received January 25, 2011
Abstract—We studied the oxidative modification of proteins and the activity of components of antioxidant sys-
tems in the blood serum of rats with different types of behavioral activity in the norm and during post-stress
psychopathology. After testing of behavior, animals were separated into four groups. We found that the groups
in the norm have different levels of oxidative modification of proteins and activity of superoxide dismutase. To
generate post-stress psychopathology, we used water-immersion stress in combination with immobilization.
After the development of post-stress psychopathology, we observed changes in the indices studied. It is possible
to conclude that different changes in oxidative modification of proteins and the activity of the antioxidant sys-
tem occur during the development of post-stress psychopathology in rats with different individual typological
particularities of behavior.
Keywords: protein oxidation, post-stress psychopathology, individual typological particularity of behavior
DOI: 10.1134/S1819712411040180
Pleiades Publishing home page | journal home page | top
If you have any problems with this server, contact webmaster.