Application Laser Transfer of Metal Nanoparticles
to Bacterial Biofilms
E. R. Tolordavaa, b, *, S. I. Kudryashovb, **, A. A. Nastulyavichusb, **,
A. A. Ioninb, **, and Yu. M. Romanova a, c, **
aGamaleya Federal Research Center of Epidemiology and Microbiology, Moscow, 123098 Russia
bLebedev Physical Institute, Moscow, 119991 Russia
cSechenov First Moscow State Medical University, Moscow, 119991 Russia
Correspondence to: *e-mail: tolordava@yandex.ru
Correspondence to: **e-mail: genes2007@yandex.ru
Received 15 September, 2019
Abstract—The method of application laser transfer of silver and copper nanoparticles for the first time has been shown to be effective against biofilms formed on a solid substrate. It has been experimentally confirmed that this effect is not associated with the influence of the laser itself. The proposed method allows one to increase the locality, availability, and efficiency of biofilm destruction due to the bactericidal effect of metal nanoparticles with a slight direct laser effect on the biofilm.
Keywords: bacterial biofilms, metal nanoparticles, laser ablation
DOI: 10.3103/S0891416819040116