Immunochemical Identification of the Protein Products
of Three New Genes from the p1314 Region
of Human Chromosome 11

A. I. Muravlev, N. A. Chikaev, A. A. Nikonova, E. M. Shelkovnikova, and N. P. Mertvetsov

Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, Novosibirsk, 630090 Russia

Received January 19, 1998

Abstract—The coding regions of unidentified cDNA TR1, TR2, and 151 mapped to the p13–14 region of
human chromosome 11 were cloned in bacterial vectors pUR290–292. Specific antisera (AS) against the
recombinant products expressed from cDNAs in bacteria were obtained. The deduced open reading frames
were shown to code for proteins actually present in human tissues. AS151 and ASTR2 specifically interacted
with 67K and 75K hydrophobic proteins, respectively, extracted from human placenta. ASTR1 revealed a 14K
protein in the soluble protein fraction of placenta.

Key words: cDNA, expression in E. coli, human genome, region p13–14 of chromosome 11

Pleiades Publishing home page | journal home page | top

If you have any problems with this server, contact webmaster.