Estimation of Shear Wave Velocity
in Gelatin Phantoms Utilizing PhS-SSOCT1
Ravi Kiran Manapurama, S. Aglyamovb, F. M. Menodiadoc, M. Mashiatullac,
Shang Wangc, S. A. Baranovc, Jiasong Lic, S. Emelianovb, and K. V. Larina, c, d, *
a Department of Mechanical Engineering, University of Houston,
N207 Engineering Building 1, Houston, TX 77204, USA
b Department of Biomedical Engineering, University of Texas at Austin,
Austin, TX, 78712, USA
c Department of Biomedical Engineering, University of Houston,
3605 Cullen Blvd, SERC Bldg, Houston, TX77204, USA
d Institute of Optics and Biophotonics, Saratov State University,
Saratov, 410012 Russia
*e-mail: klarin@uh.edu
Received February 24, 2012; in final form, May 2, 2012; published online August 1, 2012
AbstractWe report a method for measuring shear wave velocity in soft materials using phase stabilized swept
source optical coherence tomography (PhS-SSOCT). Wave velocity was measured in phantoms with various
concentrations of gelatin and therefore different stiffness. Mechanical waves of small amplitudes (~10
m)
were induced by applying local mechanical excitation at the surface of the phantom. Using the phase-resolved
method for displacement measurement described here, the wave velocity was measured at various spatially dis-
tributed points on the surface of the tissue-mimicking gelatin-based phantom. The measurements confirmed an
anticipated increase in the shear wave velocity with an increase in the gelatin concentrations. Therefore, by
combining the velocity measurements with previously reported measurements of the wave amplitude, vis-
coelastic mechanical properties of the tissue such as cornea and lens could potentially be measured.
DOI: 10.1134/S1054660X12090101
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