A Study of the Step of Alkene Activation under Ligand-Free Conditions in the Mizoroki–Heck Reaction with Unreactive Aryl Chlorides¹

A. A. Kurokhtina^a, E. V. Larina^a, E. V. Vidyaeva^a, N. A. Lagoda^a, and A. F. Schmidt^a^, *

^aDepartment of Chemistry, Irkutsk State University, Irkutsk, 664003 Russia

Correspondence to: * е-mail: aschmidt@chem.isu.ru

¹Abbreviations and designations: DMF, N,N-dimethylformamide.

Received 8 July, 2020

Abstract—The results of a kinetic study on the character (fast or slow) of a step of alkene activation in the catalytic cycle of the Mizoroki–Heck reaction with unreactive aryl chlorides in the presence of a so-called ligand-free catalytic system based on palladium are presented. An analysis of integral kinetic curves of the consumption of two competing alkenes in the reaction with aryl chloride showed that alkenes participate in a fast step of the catalytic cycle.

Keywords: Mizoroki–Heck reaction, aryl chlorides, palladium, kinetics, mechanism

DOI: 10.1134/S0023158421020051

A Study of the Step of Alkene Activation under Ligand-Free Conditions in the Mizoroki–Heck Reaction with Unreactive Aryl Chlorides1

A Study of the Step of Alkene Activation under Ligand-Free Conditions in the Mizoroki–Heck Reaction with Unreactive Aryl Chlorides¹