Chemical Features and Therapeutic Applications of Curcumin (A Review)

Aditi Aroraa, Sumit Kumara, Sandeep Kumara, Rajesh Kumarb, *, and Ashok K. Prasada, **

aBioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007 India

bDepartment of Chemistry, R.D.S College, B.R.A. Bihar University, Muzaffarpur, 842002 India

email: *rajeshenzyme@gmail.com
email: **ashokenzyme@gmail.com

Received 11 June, 2022

Abstract— Curcumin, a component of the “Golden Spice” turmeric, has been recognized for its medicinal importance since ancient times. It can be isolated from the rhizomes of Curcuma Longa, which is a member of the ginger family (Zingiberaceae). It has been used to treat various diseases due to its anti-cancer, anti-oxidant, anti-bacterial, anti-inflammatory, anti-viral, and anti-arthritic properties. However, due to its poor solubility and low bioavailability, its pharmaceutical applications are hindered. Advances have been made for its delivery techniques in order to maximize its absorption by the human body. Herein, we have provided the recent literature on the structural features and various therapeutic applications of curcumin.

Keywords: Turmeric, stability, structure activity relationship, therapeutic applications, delivery systems

DOI: 10.1134/S1070363222090201