The Electrochemical Biosensors with Paste Electrodes

V. A. Bogdanovskaya*^, **, Yu. E. Evstefeeva**, M. R. Tarasevich**,
L. N. Galitskaya***, and A. B. Galitskii***

* Institute of Biosensors, ANS, Moscow, Russia

** Frumkin Institute of Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 117071 Russia

*** Medical Instruments Department, Research Institute of Electrical Engineering, Istra, Moscow oblast, Russia

Received July 12, 1995

Abstract—The electrochemical behavior of electrodes prepared from platinum- and silver-containing pastes is
studied. The electrode based on the platinum-containing paste is shown to have properties that are close to those
inherent in the pure-platinum electrodes. It can be utilized for manufacturing electrodes for electrochemical
biosensors that employ the oxidation current of hydrogen peroxide, which is the product of an enzymatic reac-
tion, for the substrate determination. The characteristics of an electrochemical biosensor intended for determin-
ing glucose with the aid of paste electrodes are reported. The developed design of the enzyme-containing layer,
electrode batch, and electronic device allow one to determine glucose in whole blood in the concentration inter-
val 2–15 mM.

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