The Role of Neurotransmitters and Proteins
in the Genetic-Functional Organization of the Animal Brain

L. M. Gershtein

Research Institute of the Brain, Russian Academy of Medical Sciences, per. Obukha 5, Moscow, 103064 Russia

Received June 5, 2000

Abstract—It was shown that animals that differ in behavioral characteristics (August and Wistar rats) also dif-
fer in neurotransmitter and protein metabolism, which can be considered as tests that adequately reflect the
functional condition of the central nervous system. These differences are expressed at the level of both subcor-
tical structures (the hippocampus and caudate nucleus) and various morphofunctional types of the sensorimotor
cortex neurons (layers III and V). Studies on genetically different animals strains have revealed metabolic fea-
tures that allow the determination of individual behavioral features and an estimation of individual brain struc-
tures in these processes.

Key words: brain, Wistar and August rats, proteins, neurotransmitters, enzymes.

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