A Compact Microarray for Subtyping of Influenza A Virus

V. A. Ryabinin¹, E. V. Kostina, and A. N. Sinyakov

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences,
pr. Lavrent’eva 8, Novosibirsk, 630090 Russia

Received November 12, 2012; in final form, December 14, 2012

Abstract—A version of the universal oligonucleotide hybridization microchip with the size of 6 5 spots (4
4 mm) has been proposed, which operates on the principle of “one spot-one subtype.” This microchip may be
the prototype of a biosensor for fixation of influenza A virus and typing of 15 subtypes of hemagglutinin and 9
subtypes of neuraminidase.

Keywords: influenza virus A, microarray, typing, biosensor

DOI: 10.1134/S1068162013030126

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