Monocyte Subpopulations Analysis in Patients under Cardiac Surgery in Conditions of Modified Extracorporeal Circulation Using Hemodiafiltration

V. M. Zemskov^a^,*, M. N. Kozlova^a, M. S. Solovieva^a, A. V. Balbutsky^a, N. S. Shishkina^a, A. N. Kulikova^a, V. S. Demidova^a, A. M. Zemskov^b, V. A. Popov^a, G. P. Plotnikov^a, A. V. Sharanda^a, R. A. Kornelyuk ^a, and O. S. Vasiliev^c

^aVishnevsky National Medical Research Center of Surgery, Moscow, 117997 Russia

^bBurdenko Voronezh State Medical University, Voronezh, 394036 Russia

^cScientific Research Institute of Sports and Sports Medicine, Moscow, 123098 Russia

Correspondence to: *e-mail: arturrego@yandex.ru

Received 11 July, 2023

Abstract—In patients undergoing cardiosurgical operations under conditions of extracorporeal circulation, continued high-volume controlled hemodiafiltration was used, the content of subpopulations of M1, M2, M3, CD4⁺ monocytes, and total monocytes was studied in the circulation before surgery and on days 3 and 10 after it. Previously unknown data have been discovered that can be used in the diagnosis and prognosis of cardiac surgery.

Keywords: monocyte subpopulations, extracorporeal circulation, cardiac surgery

DOI: 10.1134/S2079086423090189