Dynamic Changes in the Immune Status and Biochemical Blood Markers in Patients after Cardiac Surgery with Cardiopulmonary Bypass

Abstract—A general nonspecific adaptive reaction, stress developing during the sequential implementation of the stages “anxiety,” “resistance,” and “resolution,” is considered in a limited cohort of patients who died and survived after cardiac surgery with cardiopulmonary bypass. Immune markers of the stress reaction and its ambiguous changes in patients died and discharged from the clinic with improved health are considered. Interesting innovations for changing the condition of patients are found; they can be used for assessing and predicting the outcome of cardiac surgery, as well as for substantiating immunomodulatory therapy in alternative clinical and immunological changes in the state of health.