New Magnetic Colloidal Systems Based on Biomimetic Polycomplexes
I. V. Grigoryana, c, *, V. V. Spiridonovb, A. M. Adelyanova, Yu. A. Koksharova, c, K. V. Potapenkova, I. V. Taranovc, G. B. Khomutova, c, and A. A. Yaroslavovb
aDepartment of Physics, Moscow State University, Moscow, 119991 Russia
bDepartment of Chemistry, Moscow State University, Moscow, 119991 Russia
cKotelnikov Institute of Radioengineering and Electronics, Russian Academy of Sciences, Moscow, 125009 Russia
email: *grigorian.iv19@physics.msu.ru
Received 15 May, 2023
Abstract— This paper presents new colloidal systems that have prospects for use as carriers of medicinal compounds and are polymer complexes based on polyacrylic acid molecules of various molecular weights and biogenic polyamine, additionally modified with magnetic iron oxide nanoparticles. The main physicochemical characteristics of the resulting polycomplexes are determined. The possibility of incorporating a doxorubicin medicinal compound in the polycomplexes is demonstrated, and the magnetic properties of the polycomplexes functionalized with magnetic iron oxide nanoparticles are studied.
Keywords:
polymers,
polycomplexes,
spermine,
magnetic nanoparticles,
colloidal system
DOI: 10.3103/S0027131424700135