The Telomere-Telomerase System and Mental Processes
in Aging, Norm and Pathology (Literature Review)
K. I. Pavlova, *, V. N. Mukhina, V. M. Klimenkoa, and V. N. Anisimovb
Translated by K. Lazarev
aInstitute of Experimental Medicine, St. Petersburg, 197376 Russia
bPetrov Research Institute of Oncology, St. Petersburg, 197758 Russia
Correspondence to: *e-mail: youngexp@yandex.ru
Abstract—This literature review presents results of research showing relationships between the functional activity of the telomere-telomerase system and mental (cognitive and emotional) processes in normal and various pathological states: chronic stress, depression, bipolar disorder, schizophrenia, mild cognitive impairment, and dementia in aging. It also refers to age-specific, environmental (psycho-social, economic), immunological, and genetic and epigenetic factors that influence these relationships.
Keywords: mental processes, cognitive function, intelligence, telomeres, telomerase, memory, aging, Alzheimer’s disease
DOI: 10.1134/S2079057017020114